Hygromycin B CAS: 31282-04-9 Buff phofo
| Nomoro ea lethathamo | XD90374 |
| Lebitso la Sehlahiswa | Hygromycin B |
| CAS | 31282-04-9 |
| Foromo ea limolek'hule | C20H37N3O13 |
| Boima ba Molek'hule | 527.52 |
| Lintlha tsa polokelo | 2 ho isa ho 8 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 2941900000 |
Tlhaloso ea Sehlahisoa
| Litšepe tse boima | 20mg/kg boholo |
| pH | 7-9,5 |
| Tlhahlobo | 99% |
| Tahlehelo ka ho Omisa | 5% boholo |
| mosebetsi | 950u/mg mets |
| Ammonium | 1% boholo |
| Molora o sulfated | 5% boholo |
| Ponahalo | Buff phofo |
| Purity TLC | >90% |
Botsofali ba nako ea lisele tsa tomoso hangata bo sebelisoa e le mohlala oa botsofali ba lisele tsa post-mitotic tsa motho.Yeast Saccharomyces cerevisiae e holisitsoeng ka tsoekere ka pel'a ammonium sulphate e sebelisoa haholo lipatlisisong tsa botsofali ba tomoso.Re hlahlobile botsofali ba tatellano ea tomoso ea Hansenula polymorpha e holileng maemong a hlokang metabolism ea mantlha ea peroxisome bakeng sa khōlo. The chronological lifespan of H. polymorpha e matlafatsoa ka matla ha lisele li lengoa ka methanol kapa ethanol, e hlahisoang ke li-enzyme tsa peroxisome, tse amanang le kholo ea tsoekere. seo ha se hloke peroxisomes.Nako e khuts'oane ea bophelo ba H. polymorpha ho tsoekere e bakoa haholo ke asiti e mahareng, athe ROS e kanna ea se ke ea bapala karolo ea bohlokoa.Keketseho ea lisele ho methanol/methylamine sebakeng sa methanol/ammonium sulphate e entse hore ho be le ntlafatso e eketsehileng ea bophelo.Sena se ne se sa amane le acidization e mahareng.Re bontša hore oxidation ea methylamine ka peroxisomal amine oxidase maemong a tlala ea khabone e ikarabella bakeng sa katoloso ea nako ea bophelo.Sehlahisoa sa methylamine oxidation formaldehyde se boetse se na le oxidized e fellang ka tlhahiso ea NADH, e tlatsetsang ho eketsa tlhahiso ea ATP le ho fokotsa maemo a ROS mokhahlelong o emeng.Ho feta moo, monyetla oa ho hlahisa NADH maemong a tlala ea khabone ka mohloli oa naetrojene oa organic o ts'ehetsa katoloso e eketsehileng ea nako ea bophelo ea sele.Ka lebaka leo, tlhaloso ea litlhahlobo tsa CLS ka tomoso e lokela ho kenyelletsa litlamorao tse ka bang teng ho boemo ba matla ba sele.
