Erythromycin CAS: 114-07-8 99% phofo e tšoeu ea kristale
| Nomoro ea lethathamo | XD90353 |
| Lebitso la Sehlahiswa | Erythromycin |
| CAS | 114-07-8 |
| Foromo ea limolek'hule | C37H67NO13 |
| Boima ba Molek'hule | 733.93 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29415000 |
Tlhaloso ea Sehlahisoa
| Boitsebiso | IR absorption spectrum papiso le USP RS |
| Metsi | 10% boholo |
| Ethanol | 0.5% boholo |
| Masalla a ho Ignition | 0.2% boholo |
| Tlhahlobo | 99% |
| Ho potoloha ho itseng | -71 ° ho -78 ° |
| Ponahalo | Phofo e tšoeu ea kristale |
| Crystallinity | E finyella litlhoko |
| Erythromycin B | 12.0% boholo |
| ErythromycinC | 5.0% boholo |
| Moeli oa thiocyanate | 0.3% boholo |
| Propanol | 0.5% boholo |
| N-butyl acetate | 0.5% boholo |
| Erythromycin Enol ether | 0.3% boholo |
| Lintho tse amanang le motho ka mong | 3.0% boholo |
Thutong ea hona joale, re ile ra hlahloba tšebelisano ea li-antimicrobial agents tse nang le li-membrane tsa lipid tsa mehlala tse 'nè tse etsisang li-membrane tsa lisele tsa mammalian le li-membrane tsa baktheria tsa Gram-positive le -negative le ho hlahloba li-kinetics tse tlamang ho sebelisa mokhoa oa rona oa holim'a plasmon resonance (SPR).Litšobotsi tse khethang le tse tobileng tsa ho tlama ha li-antimicrobial ho membrane tsa lipid li ile tsa hakanngoa, 'me li-parameter tsa kinetic li ile tsa hlahlojoa ka tšebeliso ea mokhoa oa ho itšoara ka linaha tse peli.Ho ile ha hlokomeloa tlhahlobo e ka ikatisang ea li-kinetics tse tlamang.Vancomyicn, teicoplanin, erythromycin, le linezolid li bontšitse tšebelisano e fokolang le li-membrane tse 'nè tsa lipid tsamaisong ea SPR.Ka lehlakoreng le leng, li-analogue tsa vancomycin li bontšitse tšebelisano le li-membrane tsa lipid tsa mohlala tsamaisong ea SPR.Litšobotsi tse ikhethileng le tse tlamang tsa li-analogue tsa vancomycin ho li-membrane tsa lipid li tšohloa ho ipapisitsoe le lintlha tsa ts'ebetso ea in vitro antibacterial le data ea rona mabapi le kamano e tlamang ea D-alanyl-D-ala robong terminus ea lebota la sele ea pentapeptide e fumanoeng ke SPR.Mochini oa ts'ebetso ea antibacterial khahlano le Staphylococcus aureus le enterococci e hananang le vancomycin e ka hlahlojoa ho sebelisoa kamano e tlamang e fumanoeng ka mekhoa ea rona ea SPR.Liphetho li bonts'a hore mokhoa oa SPR o ka sebelisoa haholo ho bolela esale pele litšoaneleho tse tlamang, joalo ka khetho le boikhethelo, tsa li-antimicrobial tse ngata ho membrane ea lipid.
