Tetracycline hydrochloride CAS: 64-75-5 99% Yellow crystalline powder
| Nomoro ea lethathamo | XD90366 |
| Lebitso la Sehlahiswa | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Foromo ea limolek'hule | C22H24N2O8 · HCl |
| Boima ba Molek'hule | 480.90 |
| Lintlha tsa polokelo | -15 ho ea ho -20 ° C |
| Khoutu ea Lekhetho e Kopantsoeng | 29413000 |
Tlhaloso ea Sehlahisoa
| Qetello | E lumellana le BP2013, EP7, USP38 |
| Litšepe tse boima | <0.005% |
| Tšilafalo e le Mong | <0.1% |
| Boitsebiso | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Tahlehelo ka ho Omisa | <2.0% |
| Mokelikeli o setseng | n-Butanol <3000ppm |
| Tlhahlobo | BP2013/EP7 99% |
| Molora oa Sulfate | <0.5% |
| Potoloho e khethehileng ea optical | -240 ho -255 ° |
| Matla | USP 38: >900ug/mg |
| Litšila ka Kakaretso | <5% |
| Ponahalo | Yellow crystalline phofo |
| 4-epianhydrotetracycline | <2% |
| Meeli ea likokoana-hloko | E lumellana |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Residual Solvent | <100ppm |
Tsoelo-pele ea ho hanyetsa likokoana-hloko e abetsoe ho feteletseng le tšebeliso e mpe ea li-antimicrobial agents.Staphylococci ke karolo ea limela tse tloaelehileng empa hape ke likokoana-hloko tse ka 'nang tsa e-ba tse hanyetsanang le lithibela-mafu tse ngata tse tsejoang.Resistance in coagulase negative staphylococci (CoNS) e khothaletsoa hore e fetohe ka lebaka la khatello e ntle ea khetho kamora kalafo ea lithibela-mafu.Phuputso ena e ile ea etsa lipatlisiso ka boteng ba li-antimicrobial agents tse robong tse sebelisoang hangata ka har'a moroto oa motho ho tsoa ho bakuli ba ka ntle lipetleleng tse peli tsa Ghana mabapi le khanyetso ea CoNS.Moroto le CoNS li ile tsa etsoa sampole (n = 246 le n = 96 ka ho latellana) ho tsoa ho bakuli ba lipetlele tse peli tsa Ghana.CoNS e ile ea khetholloa ho sebelisoa Gram staining, coagulase test, le MALDI-TOF/MS, 'me ho ba le ts'oaetso ea likokoana-hloko ho li-antimicrobial tse 12 tse sebelisoang ka tloaelo li ile tsa khethoa ke disk diffusion.Ho feta moo, ho ile ha hlahisoa mokhoa oa ho hlahloba li-antimicrobial agents tse robong tse sebelisoang haholo naheng ea Ghana ka ho sebelisa li-solid-ph ase extraction hammoho le HPLC-MS/MS ho sebelisoa ionization ea electron spray.Maqhubu a phahameng ka ho fetisisa a ho hanyetsa CoNS a ile a hlokomeloa bakeng sa penicillin V (98%), trimethoprim (67%), le tetracycline (63%).S. haemolyticus e ne e le eona isolate e tloaelehileng haholo (75%), e lateloa ke S. epidermidis (13%) le S. hominis (6%).S. haemolyticus e ne e boetse e le mofuta o bonts'ang ts'oaetso e phahameng ka ho fetisisa ea ho hanyetsa (82%).69% ea CoNS e ka thoko e ne e hanana le lithethefatsi tse ngata (≧ 4 lithibela-mafu) 'me 45% ea CoNS e ne e hanyetsa methicillin.Lithethefatsi tse thibelang likokoana-hloko li ile tsa fumanoa ho 64% ea lisampole tsa moroto tse hlahlobiloeng (n = 121) moo li-antimicrobial tse ileng tsa fumanoa hangata e ne e le ciprofloxacin (30%), trimethoprim (27%), le metronidazole (17%).Liphuputso tse kholo tsa phuputso ena e ne e le hore ho ata ha li-antimicrobial tse fumanoeng ka har'a moroto ho ne ho atisa ho feta tšebeliso e tlalehiloeng ke bakuli 'me ho ata ha S. haemolyticus e hanyetsanang e ne e le hangata ho feta mefuta e meng e hanyetsanang ea CoNS ha li-antimicrobial agents li fumanoa ka har'a moroto.
