Fluorescein 5-Isothiocyanate (isomer I) CAS:3326-32-7
Nomoro ea lethathamo | XD90514 |
Lebitso la Sehlahiswa | Fluorescein 5-Isothiocyanate (isomer I) |
CAS | 3326-32-7 |
Foromo ea limolek'hule | C21H11NO5S |
Boima ba Molek'hule | 389.38 |
Lintlha tsa polokelo | 2 ho isa ho 8 °C |
Khoutu ea Lekhetho e Kopantsoeng | 32129000 |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e mosehla e khanyang |
Tlhahlobo | 99% |
Ischemic stroke e bontšitsoe hore e baka hypermetabolism ea tsoekere ka har'a ischemic penumbra.Lintlha tsa liteko le tsa kliniki li bonts'a hore hyperglycemia e amanang le infarct ke sepheo sa kalafo se ka bang teng nakong ea stroke se matla.Leha ho le joalo, liphuputso tsa bongaka tse reretsoeng ho laola tsoekere nakong ea stroke se matla ha lia ntlafatsa sephetho sa ts'ebetso kapa ho fokotsa lefu.Kahoo, lithuto tse tsoelang pele mabapi le metabolism ea glucose bokong ba ischemic li na le mabaka a utloahalang.Re sebelisitse mohlala oa rat oa stroke o bolokang phallo ea tebeletso.Liphoofolo li ile tsa hlahlojoa ka [2-(18)F] -2-fluoro-2-deoxy-d-glucose positron emission tomography kapa imaging resonance magnetic nakong ea metsotso e 90 ea ho koaloa ha methapo e bohareng ea boko le nakong ea metsotso ea 60 ka mor'a ho tsosolosoa hape.Liphetho li ne li amahanngoa le setšoantšo sa "magnetic resonance" ea phallo ea mali ea boko, phallo ea metsi, tlhahiso ea lactate, le data ea histological mabapi le lefu la lisele le ho senyeha ha boko ba mali. -deoxy-d-glucose ho nka ka har'a li-ischemic re gions tse oelang ho infarction le sebakeng sa peri-infarct.Maiging resonance ea Magnetic e senoletse ho senyeha ha phallo ea mali ho isa maemong a ischemic ho infarct le phokotso ea phallo ea mali ea boko sebakeng sa peri-infarct.Magnetic resonance spectroscopy e senotse lactate sebakeng sa ischemic le ho ba sieo ha lactate sebakeng sa peri-infarct.Litlhahlobo tsa immunohistochemical li senotse apoptosis le ho senyeha ha mokoallo oa mali bokong ka har'a infarct. litlhoko tsa methapo ea boko ea ischemic le hypoperfused, 'me e etsahala tlas'a maemo a anaerobic le a aerobic a lekantsoeng ka tlhahiso ea lactate ea lehae.Hyperglycemia e amanang le infarct e ka thusa ho nolofatsa phepelo ea tsoekere ho boko ba ischemic.Taolo ea glycemic ka kalafo ea insulin e ka ama mokhoa ona hampe.