Cytidine Cas: 65-46-3 phofo e tšoeu ea kristale 99%
| Nomoro ea lethathamo | XD90586 |
| Lebitso la Sehlahiswa | Cytidine |
| CAS | 65-46-3 |
| Foromo ea limolek'hule | C9H13N3O5 |
| Boima ba Molek'hule | 243.22 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29349990 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu ea kristale |
| Tlhahlobo | 99% |
| Litšepe tse boima | <20ppm |
| Foromo ea Lik'hemik'hale | C9H13N3O5 |
| Tahlehelo ka ho Omisa | <0.5% |
| Masalla a ho Ignition | <0.10% |
Phepelo ea lisele tsa deoxynucleoside triphosphates (dNTPs) e bohlokoa bakeng sa boikatiso le tokiso ea DNA.Thutong ena, re batlisitse karolo ea CMP/UMP kinase (CMPK), enzyme e susumetsang sebopeho sa CDP, tokisong ea DNA.Knockdown ea CMPK e liehisa ho lokisoa ha DNA nakong ea ho hlaphoheloa ho tsoa ts'enyong ea UV liseleng tse hlokang serum empa eseng liseleng tse se nang serum ea ho hloka serum.Phepelo e sa tloaelehang ea cytidine kapa deoxycytidine e thusa ho lokisoa ha DNA e itšetlehileng ka CMPK ka lisele tse senyehileng tsa serum, ho fana ka maikutlo a hore motsoako oa dCDP kapa CDP o etsa qeto ea tekanyo ea ho lokisoa.Leha ho le joalo, ho kokota ha CMPK ha ho ame boemo bo tsitsitseng ba dCTP liseleng tse hlokang serum.Ka mor'a moo re fumane sebaka sa CMPK libakeng tsa tšenyo ea DNA le sebopeho sa eona se rarahaneng le Tip60 le ribonucleotide reductase.Tlhahlobo ea rona e bonts'itse hore N-terminal 32-amino-acid ea CMPK ea hlokahala bakeng sa ho hira libaka tsa tšenyo ea DNA ka mokhoa o itšetlehileng ka Tip60.Polelo e ncha ea mofuta o hlaha empa e se N-terminus e hlakotsoeng CMPK e khutlisa ts'ebetso ea tokiso ea DNA ka har'a lisele tse kokotang tsa CMPK.Re khothalelitse hore sebopeho sa dCDP se ikhethileng ka CMPK se fane ka mokhoa oa ho thusa tokiso ea DNA liseleng tse haelloang ke serum.
