Methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate Cas: 7355-18-2 98%
Nomoro ea lethathamo | XD90029 |
Lebitso la Sehlahiswa | methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate |
CAS | 7355-18-2 |
Foromo ea limolek'hule | C15H20O11 |
Boima ba Molek'hule | 376.31 |
Lintlha tsa polokelo | 2-8 °C |
Khoutu ea Lekhetho e Kopantsoeng | 29389090 |
Tlhaloso ea Sehlahisoa
Ponahalo | E tšoeu ho ea ho hoo e ka bang phofo e tšoeu ho kristale |
Tlhahlobo | 98% |
Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate e 'nile ea sebelisoa thutong ea ho hlahloba moralo le motsoako oa metsi a qhibilihang ka metsing a glucuronide derivatives ea camptothecin bakeng sa kankere ea prodrμg monotherapy le antibody-directed enzyme prodrμg. phekolo.E boetse e sebelisitsoe thutong ea ho etsa lipatlisiso tsa ho qaptjoa le karolo ea glycosylthio heterocycles k'hemik'hale ea lik'habohaedreite.
Synthesis ea li-derivatives tsa pentopyranic acid
N4-Benzoylcytosine 1- (methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) e fumanoe ka lihlahisoa tsa 70% ka glycosylation ea trimethylsilyl derivative ea N4-benzoylcytosine e nang le methyl 1,2 ,3,4-tetra-O-acetyl-β-D-glucopyranuronate ka pel'a tse tharo tse lekanang le SnCl4 e le moemeli oa condensing.Cytosine 1-(β-D-glucopyranosiduronamide) (IV) - the amide of pentopyranic acid - e entsoe ka lihlahisoa tse batlang li le ngata ka ammonolysis ea nucleoside (I).