Lihlahisoa

Polymer brush layers tse thehiloeng holim'a li-block copolymers tsa poly(oligo(ethylene glycol) methacrylate) (POEGMA) le poly(glycidyl methacrylate) (PGMA) li ile tsa thehoa holim'a li-wafers tsa silicon ke li-activators tse hlahisoang ke phetisetso ea elektronike ea athomo ea radical polymerization (AGET ATRP).Mefuta e fapaneng ea biomolecule e ka kopanngoa le likarolo tsena tsa borashe ka karabelo ea lihlopha tsa PGMA epoxide tse nang le lihlopha tsa amino ka har'a biomolecule, athe POEGMA, e hananang le protheine e sa hlakang, e fana ka tikoloho e thibelang litšila.Bokaholimo bo ne bo khetholloa ka sekhutlo sa metsi, ellipsometry, le Fourier transform infrared spectroscopy (FTIR) ho netefatsa karabelo ea phetoho.Karohano ea mekhahlelo ea li-block tsa copolymer ka har'a mekhahlelo e ile ea bonoa ke AFM.Phello ea thepa e ka holimo ho motsoako oa protheine e ile ea etsoa lipatlisiso ka mekhoa ea radiolabeling.Ho ile ha bontšoa hore libaka tse nang le likarolo tsa POEGMA li ne li hanana le liprotheine, athe palo ea protheine e kopantsoeng le libaka tse fetotsoeng tsa diblock copolymer e eketseha ka botenya bo ntseng bo eketseha ba PGMA.Mosebetsi oa lysozyme o kopantsoeng holim'a metsi o ka boela oa laoloa ka ho fapanyetsana botenya ba lera la copolymer.Ha biotin e kopanngoa le li-graft tsa block copolymer, bokaholimo bo ile ba lula bo hanyetsana le protheine e sa tobang empa e bonts'a tlamo e khethehileng ea avidin.Lintho tsena, ke hore, bongata bo laoloang hantle le tšebetso ea li-biomolecules tse kopantsoeng le ho khetheha ha tšebelisano le li-biomolecules tse lebisitsoeng li ka sebelisoa molemong oa ntlafatso ea karolelano ea lerata-ho-lerata lits'ebetsong tsa sensor.Ka kakaretso, libaka tse joalo li ka ba molemo e le likarolo tsa temoho ea baeloji tse nang le maemo a holimo bakeng sa lisebelisoa tse sebetsang tsa biomaterials.