Streptavidin ho tloha Streptomyces avidinii CAS:9013-20-1
| Nomoro ea lethathamo | XD90329 |
| Lebitso la Sehlahiswa | Streptavidin e tsoang ho Streptomyces avidinii |
| CAS | 9013-20-1 |
| Foromo ea limolek'hule | C14H17BrClNO2S |
| Boima ba Molek'hule | 378.71 |
| Lintlha tsa polokelo | -15 ho ea ho -20 ° C |
| Khoutu ea Lekhetho e Kopantsoeng | 35040090 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Tlhahlobo | 99% |
| Bakeng sa tšebeliso ea lipatlisiso feela, eseng molemong oa batho | lipatlisiso li sebelisoa feela, eseng molemong oa batho |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) e nang le sehlopha sa alkyne e bonts'itsoe e le sethibela se irreversible inhibitor se thehiloeng mochineng sa sialidase.Analog e sirelelitsoeng ea ester DFSA (PDFSA) ke selelekela sa DFSA se etselitsoeng ho sebelisoa liseleng tse phelang, 'me se bontšitsoe ho theha li-adducts tse kopaneng tse nang le vaerase, libaktheria le sialidase ea batho.Keketso ea enzyme ea fluorosialyl e ka hokahanngoa le biotin e kentsoeng ka azide ka ho tobetsa karabelo 'me e bonoa ke matšoao a tlaleho a khethehileng a streptavidin.Liquid chromatography-mass spectrometry/mass spectrometry analysis holim'a likhechana tsa tryptic peptide e bontša hore 3-fluorosialyl moiety e fetola masala a tyrosine a sialidase.DFSA e ne e sebelisetsoa ho bonts'a tšoaetso ea ntaramane le tlhahlobo ea ho ba le ts'oaetso ea kokoana-hloko ho seltamivir acid e khahlanong le ntaramane, athe PDFSA e ne e sebelisetsoa in situ imaging ea liphetoho tsa mosebetsi oa sialidase liseleng tse phelang.
