Cytochrome C CAS: 9007-43-6 phofo e khubelu kapa e sootho e lefifi
| Nomoro ea lethathamo | XD90330 |
| Lebitso la Sehlahiswa | Cytochrome C |
| CAS | 9007-43-6 |
| Foromo ea limolek'hule | C42H54FeN8O6S2 |
| Boima ba Molek'hule | 886.91 |
| Lintlha tsa polokelo | -15 ho ea ho -20 ° C |
| Khoutu ea Lekhetho e Kopantsoeng | 35040090 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e khubelu kapa e sootho e lefifi |
| Tlhahlobo | 99% |
| pH | 5-7 |
| Tšepe | 0.40 - 0.48% |
| Bohloeki | Ka tlase ho 90% |
| Masalla a ho Ignition | Boholo 1.5% |
| Mongobo | Ka holimo ho 6% |
| Ho beleha | E lumellana le tlhahlobo ea sterility |
| Li-pyrogens | Mahala |
| Teko ea Colorimetric | E ntle |
| E. Coli | Absent |
| Mefuta ea Salmonella | Absent |
| Sollubility 10% ka metsing | E hlakileng ka 'mala o mofubelu |
| Boleng ba ho timela | Er/Eo:Min1.1 |
| Kakaretso ea Palo ea Likokoana-hloko cfu / g | Boholo ba 100 |
| Mouta/Matomoso | Absent |
| Tšimoloho | Pelo ya pere |
Lingoliloeng tse hlahang li fana ka maikutlo a hore bisphenol A (BPA), k'hemik'hale e atileng e senyang endocrine, ha ho pepeseha ho etsahala bophelong ba pele, ho ka eketsa kotsi ea lefu la metabolism.Thutong ena, re ile ra batlisisa khopolo-taba ea hore ho pepeseha ha perinatal ho BPA ho ka etsa hore bana ba be le lefu la sebete sa mafura: ponahatso ea sebete ea metabolic syndrome, le mokhoa oa eona o ka khonehang.Litoeba tsa baimana tsa Wistar li ne li tsamaisoa ka BPA (40μg/kg/letsatsi) kapa koloi nakong ea boimana le ho anyesa.Histology ea sebete, tlhahlobo ea biochemical, transcriptome, le ts'ebetso ea mitochondrial li ile tsa hlahlojoa ho bana ba batona nakong ea pelehi ea 3, 15 le libeke tse 26.Nakong ea libeke tsa 3, morphology e sa tloaelehang ea sebete le ts'ebetso ea sebete ha ea ka ea hlokomeloa ho bana ba pepeneneng ba BPA, empa ho fokotseha ha mosebetsi oa mitochondrial breathing complex (MRC) (I le III) le liphetoho tse kholo tsa liphatsa tsa lefutso tse amehang ho metabolism ea mitochondrial fatty acid. e hlokometsoeng ha e bapisoa le litsamaiso.Libekeng tsa 15, li-micro-vesicular steatosis sebeteng, liphatsa tsa lefutso tse phahameng tse amehang litseleng tsa lipogenesis, ho eketseha ha moloko oa ROS le ho lokolloa ha Cytc ho ile ha hlokomeloa ho bana ba pepeneneng ba BPA.Joale, ho bokellana ha mafura a mangata sebeteng le serum e phahameng ea ALT ho ile ha hlokomeloa ho bana ba pepesitsoeng BPA ka libeke tse 26.Ka pono ea longitudinal, ts'ebetso ea hepatic mitochondrial e kenyelletsang ts'ebetso ea MRC, tlhahiso ea ATP, tlhahiso ea ROS le bokhoni ba membrane ea mitochondrial e ile ea mpefala butle-butle ho bana ba pepeneneng ba BPA.Ho pepesetsoa BPA ea Perinatal ho kenya letsoho ho nts'etsopele ea hepatic steatosis ho bana ba likhoto, e ka 'nang ea kena lipakeng ka ho se sebetse ha hepatic mitochondrial le metabolism ea lipid ea sebete.
