5-Methyluridine CAS: 1463-10-1 99% Phofo e tšoeu
| Nomoro ea lethathamo | XD90567 |
| Lebitso la Sehlahiswa | 5-Methyluridine |
| CAS | 1463-10-1 |
| Foromo ea limolek'hule | C10H14N2O6 |
| Boima ba Molek'hule | 258.228 |
| Lintlha tsa polokelo | 2 ho isa ho 8 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 2934999090 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Tlhahlobo | 99% |
tRNA ke sehlopha se fetotsoeng ka ho fetisisa sa mefuta ea RNA, 'me liphetoho li fumanoa ho tRNA ho tsoa linthong tsohle tse hlahlobiloeng.Leha ho na le libopeho tsa tsona tse fapaneng haholo tsa lik'hemik'hale le boteng ba tsona ho li-tRNA tse fapaneng, tse etsahalang libakeng tse fapaneng tsa tRNA, litsela tsa biosynthetic tsa liphetoho tse ngata tsa tRNA li kenyelletsa mohato(a) methylation.Litšibollo tsa morao-rao li senotse ho rarahana ho neng ho e-s'o ka ho bonoa mekhoeng ea phetoho ea tRNA, taolo le ts'ebetso ea tsona, tse fanang ka maikutlo a hore nucleoside e 'ngoe le e 'ngoe e fetotsoeng ho tRNA e kanna ea ba le ts'ebetso ea eona e ikhethileng.Leha ho le joalo, limeleng, tsebo ea rona mabapi le karolo ea liphetoho tsa tRNA ka bomong le hore na e laoloa joang e fokola haholo.Ka skrineng ea liphatsa tsa lefutso e etselitsoeng ho khetholla lintlha tse laolang ho hanyetsa maloetse le ts'ebetso ea ts'ireletso ho Arabidopsis, re khethile SUPPRESSOR OF CSB3 9 (SCS9).Liphetho tsa rona li senola SCS9 e kenyelletsa tRNA methyltransferase e hokahanyang 2'-O-ribose methylation ea mefuta e khethiloeng ea tRNA ho antico don loop.Liphetoho tsena tsa SCS9-mediated tRNA li ntlafatsa nakong ea ts'oaetso ea pathogen ea baktheria Pseudomonas syringae DC3000, le khaello ea phetoho e joalo ea tRNA, joalo ka ha ho hlokometsoe ho scs9 mutants, e beha ts'ireletso ea limela haholo khahlanong le pathogen e tšoanang ntle le ho ama pontšo ea salicylic acid (SA) tsela e laolang likarabo tsa 'mele oa ho itšireletsa mafung.Liphetho tsa rona li ts'ehetsa mohlala o fanang ka bohlokoa taolong ea liphetoho tse itseng tsa tRNA bakeng sa ho phahamisa karabelo e sebetsang ea 'mele ea ho itšireletsa mafung ho Arabidopsis, ka hona e holisa pokello ea likarolo tsa limolek'hule tsa bohlokoa bakeng sa karabelo e sebetsang ea ho hanyetsa mafu.
