Lihlahisoa

Vancomycin hydrochloride ke lithibela-mafu tsa glycopeptide 'me ke letsoai la hydrochloride la vancomycin.Ke phofo e tšoeu kapa e tšoeu e kang kristale mocheso oa kamore.Mokhoa oa eona oa ts'ebetso ke hore e ka tlama ka kamano e phahameng ho poly-terminus alanyl-alanine ea peptide ea pele e lutseng leboteng la lisele tsa baktheria, e thibela biosynthesis ea peptide glycan polymer e etsang lebota la sele ea baktheria, ka hona. ho fella ka bofokoli ba lerako la lisele le ho tsoela pele ho bolaea libaktheria.Ho phaella moo, hoa khoneha ho fetola ho phunyeletsa ha lera la baktheria, le ho thibela ka mokhoa o ikhethileng motsoako oa RNA.Sebopeho sa vancomycin hydrochloride ke phello ea eona e matla ea bactericidal khahlano le libaktheria tsa Gram-positive joalo ka Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, le streptococcus pneumoniae.E boetse e na le litlamorao tse itseng tsa anti-bacteria ho Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, le Streptococcus faecalis.Leha ho le joalo, bakeng sa libaktheria tse ngata tsa Gram-negative, Mycobacterium, Rickettsia genus, Chlamydia kapa fungus, ha e sebetse.E sebetsa ka mokhoa oa bongaka kalafong ea ts'oaetso e bakoang ke Staphylococcus aureus e hananang le methicillin le libaktheria tse ling: sepsis, endocarditis, osteomyelitis, ramatiki, kotsi ea ho chesa, ts'oaetso ea ho buuoa le ts'oaetso e 'ngoe e kaholimo, pneumonia, abscess ea matšoafo, empyema, peritonitis, meningitis, pseudomembranous colitis, le mafu a letlalo le lisele tse bonolo.Ke khetho ea mantlha bakeng sa bakuli ba alejiki ho penicillin mme ba tšoeroe ke enterococcal endocarditis le Corynebacterium (class diphtheria sp) endocarditis.