Thrombin CAS:9002-04-4
| Nomoro ea lethathamo | XD90400 |
| Lebitso la Sehlahiswa | Thrombin |
| CAS | 9002-04-4 |
| Foromo ea limolek'hule | C6H14O6 |
| Boima ba Molek'hule | 182.17 |
| Lintlha tsa polokelo | 2 ho isa ho 8 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 30021900 |
Tlhaloso ea Sehlahisoa
| Melting Point | 166-168 likhato C |
| Ponahalo | Phofo e tšoeu |
Li-sensor tsa PH li entsoe ka lifilimi tsa anodically electrodepositing iridium oxide (AEIROFs) holim'a li-microelectrodes ho li-chips 'me li koahetsoe ka poly(ethyleneimine) (PEI) bakeng sa botsitso ba mochini.Tsena li bontša karabelo ea super-Nernstian ho pH ho tloha ho pH 4.0 ho isa ho 7.7 ho buffer ea phosphate e se nang chloride.Bokaholimo ba chip bo ne bo koahetsoe ka fibronectin bakeng sa sehokelo sa lisele tsa porcine aortic endothelial (PAECs).Bokhoni ba ho sebetsa ba sensor ea pH bakeng sa ho lekola liphetoho tse matla tsa pH ea lehae bo ile ba fuputsoa ka ho susumetsa li-PAEC ka thrombin.Liphetho tsa rona li bonts'a hore thrombin e ile ea baka acute extracellular acidification ea PAECs le ho qhibiliha ha fibronectin, ho etsa hore pH ea lehae e fokotsehe.Tšebeliso ea PD98059, e leng mitogen-activated protein kinase (MAPK) inhibitor, e fokolitse acidification ea extracellular le ho eketseha ha pH ea sebaka seo.Boithuto bona bo bonts'a hore li-sensor tsa rona tsa pH li ka thusa ho etsa lipatlisiso tsa likarabo tse matla tsa cellular ho khothatso ka ho lekola liphetoho tsa nako ea 'nete tsa pH ea lisele tse hoketsoeng ho li-sensor.
