Thiamphenicol Cas: 15318-45-3
| Nomoro ea lethathamo | XD92378 |
| Lebitso la Sehlahiswa | Thiamphenicol |
| CAS | 15318-45-3 |
| Foromo ea molek'hulela | Setšoantšo sa C12H15Cl2NO5S |
| Boima ba Molek'hule | 356.22 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29414000 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu ea kristale |
| Assay | 99% mets |
| Melting Point | 163°C - 167°C |
| Litšepe tse boima | ≤10ppm |
| Tahlehelo ka ho Omisa | ≤1.0% |
| Potoloho e khethehileng ea optical | -21° - 24° |
| Chloride | ≤0.02% |
Thiamphenicol ke lithibela-mafu tse pharaletseng tsa chloramphenicol, tse sebetsang hantle ho baktheria ea gram-negative ho feta baktheria ea gram-positive.Mocheso oa kamore, ke phofo kapa kristale e tšoeu ho isa bosoeu bo bosoeu, e ka monngoang kapele le ka botlalo ke tsamaiso ea molomo, 'me e ntšoa haholo-holo ho prototype ho tsoa moroto bakeng sa metabolism.E sebelisoa ka tleliniking bakeng sa phekolo ea phefumoloho, moroto, sebete le gallbladder, typhoid le opereishene e meng ea mala, mafu a basali le mafu a ENT.Haholo-holo tšoaetsong e bonolo e sebetsa haholoanyane.E na le sebopeho sa lik'hemik'hale se tšoanang le chloramphenicol.Methil sulfone ea eona e nkile sebaka sa nitro ea chloramphenicol, e ileng ea fokotsa chefo ea eona, 'me ka vivo ts'ebetso ea eona ea antibacteria e matla ho feta chloramphenicol ka makhetlo a 2.5-5.Bakeng sa libaktheria tsa gram-positive, tse kang streptococcus pneumoniae le hemolytic streptococcus, e na le phello e matla haholo ea antibacterial, ha bakeng sa likokoana-hloko tsa gram-negative, tse kang Neisseria gonorrhoeae, meningococcus, lung Bacteroides, E. coli, Vibrio cholerae, Shigella le ntaramane, ntaramane e boetse e na le phello e matla ea antibacterial.Bakeng sa baktheria ea anaerobic, Rickettsia le amoeba, e na le phello ea antibacteria ka tekanyo e itseng.E na le mokhoa o tšoanang oa antimicrobial o nang le chloramphenicol, eo haholo-holo e thibelang motsoako oa protheine ea baktheria.Setlhare sena se monngoa ka potlako ke tsamaiso ea molomo, e fihlang tlhōrōng ea mali nakong ea lihora tse peli.Halofo ea bophelo ba eona ke lihora tse 5, e leng nako e telele ho feta chloramphenicol.Libaktheria li na le khanyetso e felletseng ho eona le chloramphenicol, ha libaktheria li na le ts'ebetso ea ho hanyetsana le eona le tetracycline.
Thiamphenicol e boetse e na le litlamorao tse matla tsa immunosuppressive, e leng ntho e ntle haholo ea immunosuppressant.Mokhoa oa eona oa ts'ebetso o fapane haholo le mahlahana a mang a immunosuppressive.Tšusumetso ea immunosuppressive e phahame ka makhetlo a 'maloa ho feta chloramphenicol.E ka ba mokhoa o atlehang oa ho fetisetsa li-transplantation le transplantation ea allogeneic.
