Rapamycin e tsoang ho Streptomyces hygroscopicus CAS:53123-88-9 E tšoeu ho ea ho e tšoeu kapa e mosehla phofo ea kristale
| Nomoro ea lethathamo | XD90356 |
| Lebitso la Sehlahiswa | Rapamycin e tsoang ho Streptomyces hygroscopicus |
| CAS | 53123-88-9 |
| Foromo ea limolek'hule | C51H79NO13 |
| Boima ba Molek'hule | 914.17 |
| Lintlha tsa polokelo | -20 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 2942000000 |
Tlhaloso ea Sehlahisoa
| Tlhahlobo | 99% |
| Ponahalo | Phofo ea kristale e tšoeu ho ea ho e tšoeu kapa e mosehla |
Rapamycin, lithethefatsi tse bontšitsoeng ho eketsa nako ea bophelo ho litoeba, li thibela sepheo sa tsela ea rapamycin (TOR), tsela e kholo e laolang kholo ea lisele le boemo ba matla.Ho 'nile ha nahanoa hore rapamycin le lithibelo tsa lijo (DR) li eketsa nako ea bophelo ka mekhoa / litsela tse tšoanang.Re sebelisa tlhahlobo ea microarray, re ile ra bapisa transcriptome ea lisele tse tšoeu tsa adipose ho tsoa ho litoeba tse fepetsoeng rapamycin kapa DR-diet bakeng sa likhoeli tse 6.Multidimensional scaling and heatmap analysis li bonts'itse hore rapamycin ha e na phello ho transcriptome ha e bapisoa le DR.Ka mohlala, litlaleho tse tšeletseng feela li ile tsa fetoloa haholo ke rapamycin ha litoeba tse feptjoang DR li bontša phetoho e kholo ho tse fetang 1000 tse ngotsoeng.Re sebelisa tlhahlobo ea tsela ea bohlale, re fumane hore stearate biosynthesis le circadian rhythm signing li fetotsoe haholo ke DR.Liphuputso tsa rona tse bontšang hore DR, empa eseng rapamycin, e na le phello ho transcriptome ea lisele tsa adipose, e fana ka maikutlo a hore mekhoa ena e 'meli e eketsa nako ea bophelo ka mekhoa / litsela tse fapaneng.
