PVP-K30 Cas: 9003-39-8 phofo e tšoeu ho ea ho mosehla o mosoeu
| Nomoro ea lethathamo | XD90232 |
| Lebitso la Sehlahiswa | PVP-K30 |
| CAS | 9003-39-8 |
| Foromo ea limolek'hule | C8H15NO |
| Boima ba Molek'hule | 141.2108 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 39059990 |
Tlhaloso ea Sehlahisoa
| Metsi | <5% |
| Litšepe tse boima | <10ppm |
| pH | 3 - 7 |
| Masalla a ho Ignition | <0.1% |
| Aldehydes | 0.05% boholo |
| Naetrojene | 11.5 - 12.8% |
| Ponahalo | Phofo e tšoeu ho isa ho bosehla bo bosoeu |
| K Boleng | 27 - 32.4 |
| Hydrazine | 1.0% boholo |
| Tlhahlobo | 99% |
Re batlisitse botsitso ba 'mele ba li-dispersions tsa amorphous curcumin le karolo ea litšebelisano tsa curcumin-polymer intermolecular ho liehisa kristale.Curcumin ke motsoako o thahasellisang oa mohlala kaha o theha likamano tsa hydrogen tsa intra le intermolecular ka kristale.Ho ile ha batlisisoa sehlopha se fapaneng sa sebopeho sa li-amorphous dispersion polymers;poly(vinylpyrrolidone), Eudragit E100, carboxymethyl cellulose acetate butyrate, hydroxypropyl methyl cellulose (HPMC) le HPMC-acetate succinate.Ho ile ha sebelisoa spectroscopy ea bohareng ba infrared ho fumana le ho lekanya boholo ba litšebelisano tsa curcumin-polymer.Ho tsitsa ha 'mele tlas'a maemo a fapaneng a tikoloho ho ne ho hlahlojoa ke phofo ea X-ray diffraction.Ho tsitsa ha lik'hemik'hale tsa Curcumin ho ne ho hlahlojoa ke UV-Vis spectroscopy.Ho itšehla thajana ha curcumin ea amorphous e tsitsitseng ho ne ho le thata ha ho se na li-polymers.Li-polymers li ipakile e le li-curcumin crystallization inhibitors tse sebetsang hantle tse nolofalletsang tlhahiso ea li-dispersions tse tiileng tsa amorphous;leha ho le joalo, li-polymers li bontšitse bokhoni bo fapaneng haholo ba ho thibela kristale nakong ea polokelo ea nako e telele.Curcumin intramolecular hydrogen bonding e fokolitse boholo ba ho tlama ha haedrojene le li-polymers;ka hona, li-polymers tse ngata e ne e se li-inhibitors tse sebetsang hantle haholo tsa crystallization.Ka kakaretso, li-polymers li ipakile e le li-crystallization inhibitors, empa thibelo e ne e lekanyelitsoe ka lebaka la intramolecular hydrogen bonding ho curcumin, e leng se lebisang ho fokotseha ha bokhoni ba li-polymers ho sebelisana le molek'hule.
