Oxytetracycline HCL Cas: 2058-46-0
| Nomoro ea lethathamo | XD91891 |
| Lebitso la Sehlahiswa | Oxytetracycline HCL |
| CAS | 2058-46-0 |
| Foromo ea molek'hulela | Setšoantšo sa C22H25ClN2O9 |
| Boima ba Molek'hule | 496.89 |
| Lintlha tsa polokelo | 0-6°C |
| Khoutu ea Lekhetho e Kopantsoeng | 29413000 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Yellow crystalline phofo |
| Assay | 99% mets |
| Sebaka se qhibilihang | 180°C |
| alpha | -188～-200°(D/20℃)(c=1,0.1mol/l HCl) (e baloang holima motheo o omisitsoeng) |
| ho qhibiliha | E qhibiliha ka bolokolohi metsing, e qhibiliha hanyenyane ka ethanol (liperesente tse 96).Litharollo tse ka metsing li fetoha lerata ha li eme, ka lebaka la ho na ha oxytetracycline. |
| PH | 2.0～3.0 (10g/l, 25℃) |
| Ho qhibiliha ha Metsi | >100 g/L |
| λmax | 360nm(H2O)(lit.) |
| E hloahloa | Khanya e Kutloha |
Oxytetracycline hydrochloride ke letsoai le lokisitsoeng ho tsoa ho oxytetracycline le nka monyetla oa sehlopha sa dimethylamino sa mantlha se protonate habonolo ho etsa letsoai ka tharollo ea hydrochloric acid.Hydrochloride ke sehlahisoa se ratoang bakeng sa lisebelisoa tsa meriana.Joalo ka li-tetracycline tsohle, oxytetracycline e bonts'a ts'ebetso e pharalletseng ea antibacterial le antiprotozoan mme e sebetsa ka ho tlama li-sub-units tsa 30S le 50S tsa ribosomal, e thibela motsoako oa protheine.
Sehlahisoa sa lithibela-mafu se arohaneng le lihlahisoa tsa actinomycete, Streptomyces rimosus, tse hōlileng ka mokhoa o loketseng.Antibacterial.
Oxytetracycline ke moriana o thibelang likokoana-hloko o bontšitsoeng bakeng sa ho phekola mafu a bakoang ke likokoana-hloko tsa Gram positive le Gram negative tse kang Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, le Diplococcus pneumoniae.E sebelisoa lithutong tsa lefutso la oxytetracycline-resistance (otrA).Oxytetracycline hydrochloride e sebelisetsoa ho ithuta fusion ea phagosome-lysosome (PL) liseleng tsa P388D1 le menyetla ea lithibela-mafu ea Mycoplasma bovis isolates.
