Iodoacetamide Cas: 144-48-9 98% Bosoeu ho isa ho bosehla bo tiileng
Nomoro ea lethathamo | XD90247 |
Lebitso la Sehlahiswa | Iodoacetamide |
CAS | 144-48-9 |
Foromo ea limolek'hule | C2H4INO |
Boima ba Molek'hule | 184.96 |
Lintlha tsa polokelo | Ambient |
Khoutu ea Lekhetho e Kopantsoeng | 29241900 |
Tlhaloso ea Sehlahisoa
Tahlehelo ka ho Omisa | <1% |
Tlhahlobo | ≥98% |
Naetrojene | 7.2 - 7.8% |
Ponahalo | Bosoeu ho isa ho bosehla bo tiileng |
Ho qhibiliha ha methanol | Ho batla ho pepenene |
Elemental Analysis Carbon | 12.5 - 13.2% |
α-Iodoacetamide ke motsoako o sebelisoang e le electrophile bakeng sa phetoho e kopanetsoeng ea masala a nucleophilic liprotheine (cysteine, methionine, histidine).Ha ho fetoloa masala a sebetsang a cysteine proteases, α-Iodoacetamide e sebetsa e le inhibitor e ke keng ea fetoloa ea li-enzyme tsena.
Lisebelisoa: E ka sebelisoa e le protease inhibitor CH2ICONH2.Joalo ka asiti ea iodoacetic, e ka thibela li-enzyme tsa SH ka mokhoa o ke keng oa fetoloa ka liketso tse latelang.R-SH+ICH2CONH2→RS-CH2CONH2+HI
Lisebelisoa: Alkylation reagents bakeng sa histidine le cysteine ho proteomics, bakeng sa tatellano ea peptide le li-enzyme inhibitors.E boetse e sebelisoa ho organic synthesis.