Glutathione e fokolitse Cas: 70-18-8 98-101% E hlakile ebile e se na 'mala
| Nomoro ea lethathamo | XD90284 |
| Lebitso la Sehlahiswa | Glutathione e fokotsehile |
| CAS | 70-18-8 |
| Foromo ea limolek'hule | Setšoantšo sa C10H17N3O6S |
| Boima ba Molek'hule | 307.32 |
| Lintlha tsa polokelo | 2 ho isa ho 8 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 29309098 |
Tlhaloso ea Sehlahisoa
| Tlhahlobo | 98% - 101% |
| Ponahalo | Phofo e tšoeu ea kristale |
| Kereiti | EP 7.0 |
| Tšilafalo A | <0.5% |
| Tšilafalo B | <0.5% |
| Litšepe tse boima | <10ppm |
| Endotoxin ea baktheria | <0.10EU/mg |
| Ho se hloeke C | <1.5% |
| Tšilafalo D | <1.0% |
| Tahlehelo ka ho Omisa | <0.5% |
| Solubility | E qhibiliha ka bolokolohi metsing, e qhibiliha hanyane ka har'a ethanol le methylene chloride |
| Tšepe | <10ppm |
| Li-chloride | <200ppm |
| Ponahalo ea Tharollo | E hlakileng ebile e se na 'mala |
| Potoloho e khethehileng ea optical | -15,5 ho -17,5 |
| Litšila ka Kakaretso | <2.5% |
| Ammonium | <200ppm |
| Molora o sulfated | <0.1% |
| Li-sulphate | <300ppm |
| Tšilafalo E | <0.5% |
Liphetoho tsa morao-rao tsa protheine, tse kang tyrosine phosphorylation, li laola litšebelisano tsa protheine-protein (PPIs) tsa bohlokoa bakeng sa ts'ebetso ea matšoao le li-phenotypes tsa cellular.Re atolositse tomoso e 'meli e nyalisitsoeng e sebelisang protheine kinases ea motho bakeng sa tlhahlobo ea li-PPI tse itšetlehileng ka phospho-tyrosine (pY) ka mokhoa o tobileng oa liteko.Re khethile 292 haholo-holo li-PPI tse itšetlehileng ka pY tse bontšang maemo a holimo mabapi le li-kinases le liprotheine tse sebetsanang le ho netefatsa karoloana e kholo litekong tsa co-immunoprecipitation tse tsoang liseleng tsa mammalian.Hoo e ka bang karolo e le 'ngoe ho tse tšeletseng ea litšebelisano li kopanngoa ke li-motif tse tlamang ka tatellano ha boholo ba li-pY-PPI li le lipakeng tsa li-epitopes tse ling kapa li laoloa ke mekhoa e meng ea temoho.Tlhahlobo ea marang-rang e senotse hore liketsahalo tsa ho lemoha pY-mediated li hokahane le mojule oa protheine e hokahaneng haholo e inehetseng ho lipontšo le litsela tsa kholo ea lisele tse amanang le mofetše.Re sebelisa litlhahlobo tse tlamang, li-protein complement ntation le phenotypic readouts ho khetholla litšebelisano tse itšetlehileng ka pY tsa TSPAN2 (tetraspanin 2) le GRB2 kapa PIK3R3 (p55γ), ka mohlala re fana ka bopaki ba hore li-PPI tse peli tse itšetlehileng ka pY li laela phenotypes tsa mofetše oa cellular.
