Boteng ba 2.8 mM D-glucose, beta-D-glucose pentaacetate (1. 7 mM) e ekelitse tokollo ea insulin ho tsoa lihlekehlekeng tse ikhethileng tsa rat pancreatic ho feta alpha-D-glucose pentaacetate.Ka mokhoa o ts'oanang, keketseho e 'ngoe ea tlhahiso ea insulin e hlahisitsoeng ke nateglinide (0.01 mM) e ne e le holimo ho lihlekehleke tse pepesehileng ho beta ho fapana le alpha-D-glucose pentaacetate.Ka lehlakoreng le leng, boteng ba 2.8 mM e sa netefatsoang ea D-glucose, alpha-L-glucose pentaacetate, empa eseng beta-L-glucose pentaacetate, tlhahiso ea insulin e ile ea eketseha haholo.Matla a phahameng a insulinotropic a beta-anomer ea D-glucose pentaacetate a tsamaellana le taba ea hore e ekelitse haholo tekanyo e pakiloeng lipakeng tsa D- [U-14C] oxidation ea tsoekere le D- [5-3H] tšebeliso ea tsoekere, athe alpha-D -glucose pentaacetate e hlotsoe ho etsa joalo.Liphuputso tsena li hlalosoa e le ho tšehetsa khopolo ea hore ho hlohlelletsa ho lokolloa ha insulin ke li-ester tsena ho bakoa haholo ke tšebelisano ea bona e tobileng le li-receptor tsa stereospecific, ka khetho ea ho hlophisoa ha C1 e tloaelehileng ho beta-D-glucose pentaacetate le alpha-L- glucose pentaacetate.
