D-Leucine Cas: 328-38-1 99% Phofo e tšoeu
| Nomoro ea lethathamo | XD90305 |
| Lebitso la Sehlahiswa | D-Leucine |
| CAS | 328-38-1 |
| Foromo ea limolek'hule | C6H13NO2 |
| Boima ba Molek'hule | 131.17292 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29224985 |
Tlhaloso ea Sehlahisoa
| Ho potoloha ho itseng | -14 ho ea ho -16 |
| AS | <1ppm |
| Pb | <10ppm |
| Tahlehelo ka ho Omisa | <0.20% |
| Tlhahlobo | 99% |
| Masalla a ho Ignition | <0.10% |
| Cl | <0.020% |
| Ponahalo | Phofo e tšoeu |
Lintlha tsa tikoloho, joalo ka sebopeho sa macronutrient lijong, li ka ba le tšusumetso e kholo kotsing ea lefu la tsoekere le metabolic syndrome.Thutong ea hona joale re bonts'a hore na ntho e le 'ngoe, e bonolo ea lijo - leucine - e ka fetola khanyetso ea insulin ka ho sebetsa liseleng tse ngata le maemong a mangata a metabolism.Litoeba li ile tsa behoa lijong tse tloaelehileng kapa tse mafura haholo (HFD).Leucine ea lijo e ile ea imena habeli ka ho phaella metsing a nooang.mRNA, protheine le lintlha tse felletseng tsa metabolomic li ile tsa hlahlojoa liseleng tse kholo tsa insulin le serum, 'me tsa amahanngoa le liphetoho ho homeostasis ea glucose le pontšo ea insulin.Ka mor'a libeke tse 8 ho HFD, litoeba li ile tsa hlahisa botenya, sebete se mafura, liphetoho tse ruruhileng lithaneng tsa adipose le insulin ho hanyetsa boemong ba phosphorylation ea IRS-1, hammoho le liphetoho tsa boemo ba metabolites ba amino acid, li-intermediates tsa TCA, glucose le cholesterol metabolites. , le mafura a acid sebeteng, mesifa, mafura le serum.Leucine ea lijo e imenneng habeli e theotse bofokoli bo bongata ba metabolite mme e bakile ntlafatso e hlakileng ea mamello ea tsoekere le pontšo ea insulin ntle le ho fetola ho ja lijo kapa boima ba 'mele.Ho eketseha ha leucine ea lijo ho ne ho boetse ho amahanngoa le ho fokotseha ha hepatic steatosis le ho fokotseha ha ho ruruha ha lisele tsa adipose.Liphetoho tsena li etsahetse leha ho na le keketseho ea phosphorylation e hlohlellelitsoeng ke insulin ea p70S6 kinase e bonts'ang ts'ebetso e ntlafalitsoeng ea mTOR, ketsahalo eo hangata e amanang le ho hanyetsa insulin.Lintlha tsena li bontša hore liphetoho tse itekanetseng sebakeng se le seng sa tikoloho / limatlafatsi li ka fetola litsela tse ngata tsa metabolism le lipontšo le ho fetola HFD induced metabolic syndrome ka ho sebetsa ka mokhoa oa tsamaiso ho li-tissue tse ngata.Lintlha tsena li boetse li fana ka maikutlo a hore ho eketseha ha leucine ea lijo ho ka fana ka tlatsetso taolong ea ho hanyetsa insulin e amanang le botenya.
