Colistin Sulfate Cas: 1264-72-8
| Nomoro ea lethathamo | XD92222 |
| Lebitso la Sehlahiswa | Colistin Sulfate |
| CAS | 1264-72-8 |
| Foromo ea molek'hulela | C52H98N16O13 |
| Boima ba Molek'hule | 1155.43 |
| Lintlha tsa polokelo | 2 ho isa ho 8 °C |
| Khoutu ea Lekhetho e Kopantsoeng | 29419000 |
Tlhaloso ea Sehlahisoa
| Ponahalo | E tšoeu ho isa ho phofo e batlang e le tšoeu |
| Assay | 99% mets |
| pH | 4-6 |
| Tahlehelo ka ho Omisa | <3.5% |
| Solubility | E qhibiliha ka bolokolohi metsing, e qhibiliha hanyenyane ka har'a ethanol (96%), hoo e batlang e sa qhibilihe ka har'a acetone trichloromethane kapa diethyl ether. |
| Sulfate | 16 - 18% |
| Potoloho e khethehileng ea optical | -63 ho ea ho -73 |
| Litšila ka Kakaretso | <23% |
| Molora o sulfated | <1% |
| Potency (motheo o omisitsoeng) | >19000u/mg |
1.Ke lithibela-mafu tsa motheo tsa peptide, haholo-holo bakeng sa thibelo le phekolo ea mafu a tšoaetsanoang le ho khothalletsa kholo ea liphoofolo.
2.E ka kopanngoa le lera la lipoprotein phosphate mahala, ho etsa hore tsitsipano ea lera holim'a lisele e fokotsehe, e eketsehe ho phunyeletsa, ho fella ka ho tsoa ha cytoplasm ea lefu la sele.
3.E na le phello e matla ea ho thibela likokoana-hloko khahlanong le libaktheria tsa gram-negative (haholo-holo E. coli, Salmonella, Pseudomonas aeruginosa, Proteus le Haemophilus, joalo-joalo), ha e na phello ho libaktheria tsa Gram-positive (Staphylococcus aureus le ntle le hemolytic streptococcus ka ntle) li-fungus.
4. Colistin sulfate oral e thata ho monya, ha e chefo, e bonolo ho baka masala a lithethefatsi, ho bonolo ho hlahisa ho hanyetsa lithethefatsi.
