BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT Cas: 100929-71-3
| Nomoro ea lethathamo | XD90431 |
| Lebitso la Sehlahiswa | BETA-NADPH TETRA(CYCLOHEXYLAMMONIUM) LETSWAI |
| CAS | 100929-71-3 |
| Foromo ea limolek'hule | C21H30N7O17P3.4[C6H13N] |
| Boima ba Molek'hule | 1142.11748 |
| Lintlha tsa polokelo | -20 °C |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Tlhahlobo | 99% |
NADPH oxidase ke lelapa la li-enzyme tse hlahisang mefuta e sa tšoaneng ea oksijene (ROS).NOX1 (NADPH oxidase 1) le NOX2 oxidase ke mehloli e meholo ea ROS leboteng la methapo maemong a kang khatello ea mali, hypercholesterolaemia, lefu la tsoekere le botsofali, ka hona ke karolo ea bohlokoa ea khatello ea oxidative, ho se sebetse hantle ha endothelial le ho ruruha ha methapo ea mali. ntlafatso ea methapo ea kutlo le atherogenesis.Tlhahlobisong ena, re ntšetsa pele mohopolo o bapisoang le tšebeliso ea li-antioxidants tse tloaelehileng, ho thibela NOX1 le NOX2 oxidase ke mokhoa o phahameng oa ho loants'a khatello ea oxidative.Re hlalosa ka bokhuts'oane tse ling tse tloaelehileng le tse ntseng li hlaha tsa NADPH oxidase inhibitors.Ntle le moo, re totobatsa karolo ea bohlokoa ea karolo ea taolo ea NADPH oxidase, p47phox, ts'ebetsong ea li-oxidase tsa vascular NOX1 le NOX2, 'me re fana ka maikutlo a hore na kutloisiso e ntle ea litšebelisano tsa eona tse khethehileng tsa limolek'hule e ka thusa joang nts'etsopele ea lithethefatsi tse ikhethileng tsa isoform ho thibela. kapa ho phekola mafu a pelo ea pelo.
