Lihlahisoa

3-Fluoro-4'-propyl-biphenylboronic acid ke motsoako oa lik'hemik'hale oo e leng oa sehlopha sa boronic acid.E na le lesale la biphenyl le sehlopha sa propyl se khomaretsoeng pheletsong e 'ngoe le athomo ea fluorine e khomaretsoeng ka lehlakoreng le leng, hammoho le sehlopha sa boronic acid.Motsoako ona o na le likopo tse 'maloa masimong a motsoako oa manyolo, k'hemistri ea meriana, le mahlale a lisebelisoa.E 'ngoe ea lisebelisoa tse ka sehloohong tsa 3-Fluoro-4'-propyl-biphenylboronic acid ke e le coupling reagent ho organic synthesis.Hangata e sebelisoa ho Suzuki-Miyaura cross-coupling reactions, e leng mekhoa e matla ea ho etsa li-carbon-carbon bond.Motsoako ona o sebetsa e le boronate ester, e sebetsanang le aryl kapa vinyl halides tlas'a palladium catalysis ho etsa metsoako ea biaryl kapa styryl.Ho ba teng ha athomo ea fluorine le sehlopha sa propyl mohahong ho ka susumetsa ts'ebetso le khetho ea mokhoa oa ho kopanya li-cross-coupling, e leng se etsang hore e be mohaho o nang le mekhoa e metle bakeng sa motsoako oa limolek'hule tse rarahaneng tsa limolek'hule. -4'-propyl-biphenylboronic acid e ka sebelisoa bakeng sa ho qapa le ho kopanya metsoako ea likokoana-hloko.Ho ba teng ha sehlopha sa boronic acid ho lumella hore ho thehoe litlamo tsa covalent tse khutlisetsoang morao le li-biomolecules, joalo ka li-enzyme kapa liprotheine tsa receptor.Lik'hemik'hale tsena li tsejoa e le boronate-based inhibitors 'me li ka sebelisoa ho lebisa li-enzyme tse itseng tse amehang mafu a kang kankere kapa lefu la tsoekere.Athomo ea fluorine le sehlopha sa propyl se ka boela sa thusa ho ntlafatsa thepa ea meriana ea metsoako ena, e kang potency, selectivity, le metabolic stability.Ho phaella moo, 3-Fluoro-4'-propyl-biphenylboronic acid e na le lisebelisoa tse ka sebelisoang ho saense ea thepa.Li-acid tsa boronic li tsejoa ka bokhoni ba tsona ba ho itšoara ka diol kapa polyols, ho theha maqhama a matla a covalent.Thepa ena e ka sebelisoa hampe tšimong ea mahlale a polymer ho etsa lisebelisoa tsa ho ipholisa kapa likopano tsa supramolecular.Ka ho kenyelletsa motsoako ona ho li-polymers kapa li-coatings, bafuputsi ba ka hlahisa ts'ebetso ea boronic acid, e leng ho lumellang hore ho be le likamano tse tsosolositsoeng le monyetla oa ho lokisa tšenyo kapa ho tsosolosa thepa ea mechine. ka lisebelisoa tsa organic synthesis, k'hemistri ea bongaka, le mahlale a thepa.Li-reactivity tsa eona le lihlopha tse ikhethang tse sebetsang li fana ka menyetla ea ho thehoa ha carbon-carbon bonds ka likarabelo tse kopanyang, ho qaptjoa le ho kopanya metsoako e sebetsang ea biologically, le ho theha lisebelisoa tse matla.Lihlopha tsa fluorine le propyl li ntlafatsa ts'ebetso ea motsoako le ho susumetsa thepa ea eona ea meriana kapa ea lintho tse bonahalang.Likarolo tsena li etsa hore 3-Fluoro-4'-propyl-biphenylboronic acid e be sesebelisoa sa bohlokoa bakeng sa bo-ramahlale le bafuputsi ba liindasteri tse fapaneng, se kenyang letsoho tsoelopeleng ea ho sibolla lithethefatsi, boenjiniere ba thepa, le mafapha a mang a amanang.