Lihlahisoa

1-(2-Pyridyl) piperazine, eo hape e tsejoang e le 2-(1-Piperazinyl)pyridine, ke motsoako oa lik'hemik'hale o fumanang mekhoa e sa tšoaneng ea lisebelisoa tšimong ea organic synthesis le chemistry ea meriana.E 'ngoe ea lisebelisoa tsa mantlha tsa 1-(2- Pyridyl) piperazine e tšoana le mohaho o nang le mekhoa e mengata ea ho haha ​​​​motsoako oa metsoako ea bioactive.E sebetsa e le karolo ea bohlokoa ea ho lokisa lithethefatsi tse lebisitseng tsamaiso ea methapo e bohareng, ho kenyelletsa li-antipsychotics, li-antidepressants le li-antihistamine.Ho ba teng ha lihlopha tse peli tsa piperazine le pyridine mohahong oa eona ho lumella ho kenyelletsoa ha lihlopha tse itseng tse sebetsang le liphetoho ho lokisa thepa ea molek'hule ea ho qetela ea lithethefatsi. e ithutiloe bakeng sa mesebetsi ea eona ea meriana le litlamorao tsa bioloji.E bonts'itse litšebelisano le li-receptor tse fapaneng bokong, joalo ka li-receptor tsa serotonin, li-dopamine receptors, le li-adrenergic receptors.Litšebelisano tsena li lebisitse lipatlisisong mabapi le mekhoa ea eona ea phekolo e ka 'nang ea e-ba teng bakeng sa maemo a kang lefu la methapo ea kutlo le maemo a bophelo bo botle ba kelello.Ho feta moo, 1-(2-Pyridyl) piperazine e 'nile ea hlahlojoa e le ligand ka k'hemistri ea ho hokahanya ka lebaka la bokhoni ba eona ba ho hokahanya le li-ion tsa tšepe. .Thepa ena e lebisitse ho kopanngoeng ha lisebelisoa tsa tšepe tse nang le ts'ebeliso e ka bang teng ho catalysis le mahlale a thepa.Ho bohlokoa ho hlokomela hore le ha 1-(2-Pyridyl) piperazine e bonts'itse lits'ebetso tse ts'episang mafapheng a fapaneng, mehato e nepahetseng ea ts'ireletso e tlameha ho nkuoa ha e sebetsa. ka eona.Sena se kenyelletsa ho shebana le lipampiri tsa lintlha tsa polokeho, ho roala lisebelisoa tse nepahetseng tsa ts'ireletso, le ho latela mekhoa ea lab e thehiloeng ho netefatsa ts'ebetso e bolokehileng le ho fokotsa likotsi tse ka bang teng.Ho feto-fetoha ha eona e le mohaho oa mohaho o lumella hore ho be le motsoako oa metsoako ea bioactive e lebisang tsamaiso ea methapo e bohareng.Ntle le moo, mesebetsi ea eona ea litlama le lits'ebetso tse ka bang teng tsa kalafo li e etsa sebaka sa thahasello bakeng sa lipatlisiso tse ling.Leha ho le joalo, mehato ea tšireletso e lokela ho lateloa kamehla ha ho sebetsa le motsoako ona.