Lihlahisoa

Tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate ke motsoako oa lik'hemik'hale o tsejoang ka mefuta e fapaneng ea ts'ebeliso ea ona ho organic synthesis le chemistry ea meriana.Ka sebopeho sa eona se ikhethang sa limolek'hule, motsoako ona o na le thepa e khahlang le ts'ebeliso e ka bang teng mafapheng a fapaneng a lipatlisiso.E 'ngoe ea lisebelisoa tsa mantlha tsa tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate ke tšebeliso ea eona joalo ka moaho. thibela ka har'a organic synthesis.Pyrazolo [1,5-a] scaffold ea pyridine, e kopantsoeng le lihlopha tse sebetsang tsa carbamate le acetyl, e fana ka monyetla oa ho kenyelletsa motsoako ona ho kopanya limolek'hule tse rarahaneng.E ka sebelisoa e le thepa ea ho qala bakeng sa kaho ea metsoako ea heterocyclic, li-intermediate tsa meriana, kapa lihlopha tse ling tsa bohlokoa tsa manyolo. le ho sibolla lithethefatsi.Ho ba teng ha pyrazolo [1,5-a] pyridine core e fana ka maikutlo a bokhoni ba eona e le pharmacophore, sebopeho sa sebopeho se ikarabellang bakeng sa ts'ebetso ea likokoana-hloko ea lithethefatsi.Ka ho fetola li-substituents ho lihlopha tsa carbamate kapa acetyl, hoa khonahala ho hlahloba likamano tsa ts'ebetso le ho ntlafatsa thepa ea pharmacological ea komporo.Motsoako ona o ka hlahlojoa khahlanong le lipheo tse fapa-fapaneng tsa likokoana-hloko, tse kang li-enzyme kapa li-receptors, ho khetholla metsoako e ka 'nang ea e-ba teng bakeng sa nts'etsopele ea lithethefatsi tse ncha.Ho feta moo, tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate e sebetsa e le sesebelisoa se molemo lipatlisisong tsa baeloji ea lik'hemik'hale, e nolofalletsang boithuto ba lits'ebetso tsa baeloji le likamano tsa limolek'hule.Sebopeho sa eona se ikhethileng, se kopantsoeng le monyetla oa ho hlahisa li-tag kapa lihlopha tse sebetsang hantle, li ka thusa ho ngola le ho latella li-biomolecule tse itseng, joalo ka liprotheine kapa li-nucleic acid, litekong tsa cellular kapa tsa biochemical.Motsoako ona o ka thusa bafuputsi ho hlakisa litsela tsa likokoana-hloko, litšebelisano tsa liprotheine le liprotheine, kapa mokhoa oa ts'ebetso ea phekolo e ka 'nang ea e-ba teng.Ho feta moo, tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate e ka fumana lits'ebetso ho saense ea lintho tse bonahalang, haholoholo ntshetsopeleng ya disebediswa tsa tshebetso kapa dae.Thepa ea eona ea elektroniki le steric e ka hlophisoa ho kenya letsoho moetsong oa thepa e nang le thepa e lakatsehang ea optical, ea motlakase kapa ea mochini.Ka mohlala, e ka kenngoa ka har'a moralo oa li-semiconductors tse phelang kapa tsa sebelisoa e le chromophore ka li-diode tse hlahisang leseli kapa lisele tsa letsatsi.Ka kakaretso, tert-butyl 3-acetylpyrazolo[1,5-a]pyridin-5-ylcarbamate e kopantsoe le lits'ebetso tse ngata ho organic synthesis, k'hemistri ea bongaka, biology ea lik'hemik'hale, le saense ea lintho tse bonahalang.Sebopeho sa eona se ikhethang le lihlopha tse sebetsang li fana ka motheo oa ho kopanya limolek'hule tse rarahaneng, nts'etsopele ea meriana e mecha, thuto ea mekhoa ea likokoana-hloko, le moralo oa lisebelisoa tse sebetsang.Litšebeliso tse fapaneng tsa komporo ena li totobatsa bohlokoa ba eona libakeng tse fapaneng tsa lipatlisiso le bokhoni ba eona ba ho kenya letsoho ntlafatsong ea mahlale le thekenoloji.