Lihlahisoa

(3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ke motsoako oa lik'hemik'hale o nang le mekhoa e sa tšoaneng ea ho etsa lipatlisiso tsa tlhaho le lipatlisiso tsa meriana.Sebopeho sa eona se ikhethang sa limolek'hule, se nang le selikalikoe sa pyrrolidine se nang le tert-butyl le ethyl substituents, hammoho le mesebetsi ea carboxylate, e fana ka thepa e thahasellisang le mekhoa e ka sebelisoang.E 'ngoe ea lisebelisoa tsa mantlha tsa (3R,4S) -1-tert-Butyl 3- ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ke karolo ea eona e le moaho oa chiral ka har'a organic synthesis.Ho ba teng ha li-stereocenters libakeng tsa 3R le 4S ho fana ka monyetla oa ho etsa limolek'hule tse rarahaneng tse nang le stereochemistry e itseng.Motsoako ona o ka sebetsa e le ntho e qalang bakeng sa ho qaptjoa ha metsoako e sa tšoaneng ea chiral, e kang li-intermediate tsa meriana, lihlahisoa tse rarahaneng tsa tlhaho, le lik'hemik'hale tsa agrochemicals. 3-dicarboxylate hydrochloride e ka sebelisoa e le sesosa kapa ligand ho catalysis ea asymmetric.Mokokotlo oa eona oa chiral pyrrolidine o ka etsa hore motho a be le maikutlo a lerato le a ts'oanelang ho khothaletsa liketso tse khethiloeng.Motsoako ona o ka sebelisoa ka liphetoho tse sa tšoaneng, tse kang enantioselective synthesis ea limolek'hule tsa manyolo, li-intermediates tsa meriana, le metsoako e meng ea bohlokoa.Ho feta moo, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3- dicarboxylate hydrochloride e na le ts'ebeliso e ka bang teng lipatlisisong tsa k'hemistri ea meriana.Likarolo tsa eona tsa sebopeho le litšoaneleho tsa li-chiral li e etsa sesebelisoa sa bohlokoa ho nts'etsopele ea litlhare tse ncha.Motsoako ona o ka sebelisoa ho hlahloba likamano tsa ts'ebetso ea sebopeho, ho ntlafatsa thepa ea meriana, le ho ntlafatsa ts'ebetso ea likokoana-hloko kapa khetho ea lipakane tse khethehileng tsa lithethefatsi.Ho feta moo, (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1, 3-dicarboxylate hydrochloride e ka kenyelletsoa lilaebraring tsa metsoako bakeng sa tlhahlobo e phahameng ea lisebelisoa mananeong a ho sibolla lithethefatsi.Lilaebrari tsena tse kopaneng li ka lekoa khahlano le lipheo tse fapaneng tsa baeloji ho fumana metsoako e ka bang teng ea lead le batho ba ka sebelisang lithethefatsi.Sebopeho sa chiral sa motsoako ona se ka kenya letsoho ho sibolloe lisebelisoa tse ncha tsa phekolo tse nang le thepa e ntlafetseng ea phekolo ea meriana. e kopantsoe le lits'ebetso ho organic synthesis le lipatlisiso tsa meriana.Litšobotsi tsa eona tsa sehlopha sa chiral le tse sebetsang li etsa hore e be mohaho oa bohlokoa oa mohaho bakeng sa motsoako oa limolek'hule tse rarahaneng le ho catalysis ea asymmetric.Ho feta moo, bokhoni ba eona ba lipatlisiso tsa k'hemistri ea meriana le mananeong a sibollo ea lithethefatsi bo totobatsa bohlokoa ba eona ho nts'etsopele ea metsoako e mecha ea meriana.Lintho tse fapaneng le tse ikhethang tsa (3R,4S) -1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride e etsa hore e be letlotlo la bohlokoa lefapheng la chemistry ea tlhaho, lipatlisiso tsa meriana, le nts'etsopele ea lithethefatsi.