Nystatin dihydrate CAS: 1400-61-9 Nystatin A1 > 85%;metsoako efe kapa efe e meng
Nomoro ea lethathamo | XD90352 |
Lebitso la Sehlahiswa | Nystatin dihydrate |
CAS | 1400-61-9 |
Foromo ea limolek'hule | C47H75NO17 · 2H2O |
Boima ba Molek'hule | 962.10 |
Lintlha tsa polokelo | -15 ho ea ho -20 ° C |
Khoutu ea Lekhetho e Kopantsoeng | 29419000 |
Tlhaloso ea Sehlahisoa
Qetello | E lumellana le Ph.Eur.9.7 |
Pseudomonas aeruginosa | Absent |
pH | 6.0-8.0 (3% tharollo e nang le metsi) |
Tlhahlobo | Nystatin A1>85%;metsoako efe kapa efe e meng <4% |
Tahlehelo ka ho Omisa | <5.0% |
Ponahalo | Phofo e mosehla kapa e sootho |
Molora o sulfated | <3.5% |
Tlhahlobo ea ID D | E lumellana (UV) |
TAMC | <1000cfu/g |
TYMC | <100cfu/g |
Staphylococcus Aureus | Absent |
Methanol e setseng ea Solvent | <3000ppm |
Mesityloxide | <500ppm |
Residual Solvent | <5000ppm |
Tlhahlobo ea Boitsebiso (UV) A | e tshoanang le tshupiso |
Absorbance A305 | >0.6 |
baktheria ea gram-negative e mamellang bile (E.coli + Salmonella sp.) | Absent |
Mefuta ea Clostridia | Absent |
Metsoako e setseng (1-butanol) | <1000ppm |
Bohloeki;Tekolo ea Microbial | NLT> 4400 IU/mg motheong o omisitsoeng |
Ho fumana mefuta e fapaneng ea kliniki ho khetholla invasive pulmonary aspergillosis (IPA) ho tloha colonization ho bakuli ba nang le lefu la matšoafo le sa foleng le setso se setle sa Aspergillus spp.ka disampole tsa phefumoloho.Thuto ya Retrospective cohort ho kenyeletswa le bakudi ba nang le ho ikarola ho hema ba Aspergillus spp.nakong ea lilemo tse 10.IPA e ile ea hlahlojoa ho latela mekhoa ea Bulpa.Ho ile ha bokelloa mefuta e fapaneng ea meriana 'me ho ile ha etsoa tlhahlobo e ngata ea ho fokotseha ha thepa.Bakuli ba mashome a robeli a metso e meraro ba nang le ho itšehla thajana ho Aspergillus spp.ho tloha lisampole tsa phefumoloho li ne li kenyelelitsoe;68.7% (n = 57) ea bakuli ba ne ba e-na le lefu le sa foleng la pulmonary, 18% (n = 15) pulmonary fibrosis le 13.3% (n = 11) asthma ea bronchial.Bakuli ba mashome a mabeli a metso e 'meli (26.6%) ba ne ba e-na le IPA.Tšebeliso ea fluconazole (OR 4.49; CI 95% 1.5-13.4; P = .007), ho hloleha ho matla ha phefumoloho (OR 4.64; CI 95% 1.46-14.72; P = .009) le nako ea ho kena sepetlele (OR 1.05; CI 95% 1.01-1.1; P=.006) e ne e amahanngoa le IPA. Tšebeliso ea pele ea fluconazole, ho hloleha ho matla ha phefumoloho le nako ea ho kena sepetlele li amahanngoa le IPA ho bakuli ba nang le lefu la matšoafo le sa foleng le ho itšehla thajana ha Aspergillus spp.Copyright © 2012 Elsevier España, SL Litokelo tsohle. boloketsoe