Lihlahisoa

Europium(III) le terbium(III) complexes, e leng [Eu(dpq)(DMF)2(NO3)3] (1), [Eu(dppz)2(NO3)3] (2), [Tb(dpq) )(DMF)2Cl3] (3), le [Tb(dppz)(DMF)2Cl3] (4), moo dipyrido[3,2-d:2',3'-f]quinoxaline (dpq ho 1 le 3) , dipyrido[3,2-a: 2',3'-c] phenazine (dppz ka 2 le 4) le N, N'-dimethylformamide (DMF) li 'nile tsa aroloa, tse khetholloang ho tloha boitsebisong ba bona ba physicochemical, lithuto tsa luminescence le ho sebelisana ha tsona. ka DNA, serum albumin protein le photo-induced DNA cleavage activity lia ithutoa.Mehaho ea kristale ea X-ray ea li-complexes 1-4 e bonts'a meaho e thehiloeng ho mononuclear Ln (3+).The Eu(3+) ho [Eu(dpq)(DMF)2(NO3)3] (1) le [Eu(dppz)2(NO3)3] (2) e le [Eu(dppz)2(NO3)3) ]·dppz (2a) e amohela sebopeho sa li-dodecahedron tse hokahaneng tse leshome tse nang le bidentate N,N-donor dpq ligand, DMF tse peli le li-anion tse tharo tsa NO3(-) ho 1 le li-bidentate tse peli tsa N,N-donor dppz ligand le tse tharo NO3( -) anions ho 2. Complexes 3 le 4 li bonts'a sebopeho sa octahedron e kopantsoeng ka mono-capped e supileng moo Tb(3+) e nang le li-bidentate dpq/dppz ligands, DMF tse peli le tse tharo tsa Cl(-) anions.Li-complexes li na le khanya e ngata ea tlhaho e bontšang phetisetso ea matla a foto-thabelo e sebetsang ho tloha dpq/dppz antenna ho ea Ln(3+) ho hlahisa maemo a thabo a nako e telele bakeng sa liphetoho tsa f → f.Lekhalo le rarollotsoeng ka nako la li-complexes 1-4 li bonts'a mefuta e menyenyane ea khase e hlahisoang ke (5)D0 → (7)F(J) le (5)D4 → (7)F(J) ff liphetoho tsa Eu(3) +) le Tb(3+) ions ka ho latellana.Palo ea limolek'hule tsa metsi a ka hare-hare (q) e ile ea khethoa ho tloha litekanyo tsa bophelo ba luminescence ho H2O le D2O e tiisang maikutlo a ligand-exchange ka metsi a tharollo.Li-complexes li bonts'a tšekamelo e kholo ea tlamahano ho CT-DNA e fanang ka boleng bo tlamang bo sa feleng sebakeng sa 1.0 × 10(4) -6.1 × 10(4) M(-1) ka tatellano ea 2, 4 (dppz)> 1, 3 (dpq).Lintlha tse tlamang tsa DNA li fana ka maikutlo a hore DNA groove e tlamahane ka mokhoa o sa fellang oa ho kopana ha li-complexes.Li-complexes kaofela li boetse li bontša tšekamelo e tlamang (K(BSA) ~ 10(5) M(-1)) ho protheine ea serum ea bovine albumin (BSA).Botebo ba lihlopha tsa spectral tsa luminescence tse nang le nako bo ntse bo eketseha haholo ha DNA e ntse e eketseha sebakeng se nang le metsi a metsi ka lebaka la ho falla ha metsi ha a sebelisana le DNA, kahoo a fokotsa ho tima ho se nang mahlaseli ka OH oscillator.Complexes 1-4 e phunya supercoiled (SC) ds-DNA to its nicked circular (NC) ha e pepesehetse UV-A lebone la 365 nm ka ho theha singlet oxygen ((1)O2) le hydroxyl radicals (HO˙) joalo ka mefuta ea oksijene e sebetsang maemong a micromolar tlasa maemo a fisioloji.