Lipase ho tloha manyeme a porcine CAS: 9001-62-1 Brown ho ea phofo ea beige
Nomoro ea lethathamo | XD90387 |
Lebitso la Sehlahiswa | Lipase ho tsoa ho manyeme a porcine |
CAS | 9001-62-1 |
Foromo ea limolek'hule | N/A |
Boima ba Molek'hule | N/A |
Lintlha tsa polokelo | 2 ho isa ho 8 °C |
Khoutu ea Lekhetho e Kopantsoeng | 35079090 |
Tlhaloso ea Sehlahisoa
Molora | <12% |
AS | <2mg/kg |
Pb | <2mg/kg |
Litaba tsa Metsi | <8% |
Tlhahlobo | 99% |
Ts'ebetso ea enzyme | >30000u/g |
Ponahalo | Brown ho beige phofo |
Sehlopha sa Coliform | <30MPH/100g |
Bakeng sa tšebeliso ea lipatlisiso feela, eseng molemong oa batho | lipatlisiso li sebelisoa feela, eseng molemong oa batho |
Phetoho ea triglyceride (TG) metabolism liseleng tsa vascular smooth muscle (SMC) e ka 'na ea amana le phenotype e itseng, le hoja sena ha se e-s'o hlakisoe.Adipose triglyceride lipase (ATGL) e fana ka ts'ebetso e kholo ea TG ho lisele tsa adipotic le tse seng tsa adipotic.Thutong ea hona joale, re arolelitse SMC ho litoeba tse haelloang ke ATGL (ATGL(-/-)mSMC).ATGL(-/-)mSMC e bonts'itse ho bokella TG ka boithatelo ka karabelo e tlase ea mitogenic le polelo ea mesifa e boreleli ea actin (SMA) ha e bapisoa le ATGL (+/+) mSMC.Peresente ea lisele tse ntle tsa _-galactosidase tse amanang le senescence le tsona li eketsehile ho ATGL(-/-) mSMC.PCR ea nako ea 'nete e lateloa ke ho hlahlojoa ka tlhahlobo ea DNA e tsepamisitsoeng e senotse polelo e laoloang ka holimo ea glucokinase (1.7-fold), lipoprotein lipase (3.8-fold) le interleukin-6 (3.7-fold) le polelo e tlase e laoloang ea kholo ea vascular endothelial. factor-A (0.2-fold), mofuta oa I collagen (0.5-fold), le ho fetola sekhahla sa kholo-_ (0.4-fold) ho ATGL (-/-) mSMC bapisoa le ATGL (+/+) mSMC.Ka mor'a moo, ectopic gene transfer ea ATGL ea motho e ile ea lekoa ho sebelisa doxycycline (Dox) -regulatable myc-DDK-tagged adenovirus vector (AdvATGL).Tšoaetso ea AdvATGL e ile ea fella ka ho fokotseha ha TG ho bokellana ka karabo e phahameng ea mitogenic le polelo ea SMA, 'me ea fokotseha ka linomoro tsa lisele tsa senescent ho ATGL (-/-) mSMC.Ho feta moo, mokhoa o khelohileng oa polelo ea liphatsa tsa lefutso ho ATGL(-/-)mSMC o ne o ka lokisoa.Lintlha tsa rona li fana ka maikutlo a hore ATGL (-/-) mSMC e na le phenotype e ikhethang e ka 'nang ea amana le lefu la vascular pathogenesis.Plasticity ea SMC phenotypes e amanang le metabolism ea lipid e ka ba sepheo sa kalafo.