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Lihlahisoa

L-Methionine Cas: 63-68-3 99% White crystalline phofo

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD90287
Cas: 63-68-3
Foromo ea molek'hule: C5H11NO2S
Boima ba Molek'hule: 149.21134
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana: 1kg USD20
Sephutheloana sa Bongata: Kopa Quote

 

 

 

 

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD90287
Lebitso la Sehlahiswa L-Methionine

CAS

63-68-3

Foromo ea limolek'hule

C5H11NO2S

Boima ba Molek'hule

149.21134
Lintlha tsa polokelo Ambient

Khoutu ea Lekhetho e Kopantsoeng

29304010

 

Tlhaloso ea Sehlahisoa

Tlhahlobo 98% - 101.5%
Ponahalo Likristale tse tšoeu kapa phofo ea crystalline
Qetello  
Boitsebiso E kopana le tlhoko
pH 5.6 - 6.1
Tahlehelo ka ho Omisa ≤ 0.3%
Sulfate (SO4) ≤ 0.03%
Tšepe ≤ 0.003%
Masalla a ho Ignition ≤ 0.4%
Chloride ≤ 0.05%
Tšepe e boima ≤ 0.0015%
Chromotograhic Bohloeki Ha ho fete 2.0% ea litšila tsohle tse fumanoang
Potoloho e khethehileng [ α ] D 2 5 +22.4º ~ +24.7º

 

Lithuto tsa rona tse fetileng li senotse likarolo tsa eona tsa bohlokoa maemong a pele le a morao-rao a ts'oaetso ea KSHV.Thutong ena, re hlahlobile interactome ea ORF45 re sebelisa sehlopha sa li-antibodies tsa monoclonal.Ho phaella ho liprotheine tse tsejoang pele tsa extracellular regulated kinase (ERK) le p90 ribosomal S6 kinase (RSK), re fumane liprotheine tse ling tse 'maloa tse kopantsoeng, ho akarelletsa le tse hlaheletseng tsa ~ 38 kDa le ~130 kDa.Mass spectrometry e senoletse hore protheine ea 38-kDa ke kokoana-hloko ORF33 le protheine ea 130-kDa ke cellular USP7 (ubiquitin-specific protease 7).Re ile ra etsa 'mapa oa sebaka se tlamang sa ORF33 ho carboxyl-terminal 19 amino acid (aa) e bolokiloeng haholo ea ORF45 le sebaka se tlamang sa USP7 ho sepheo se tlalehiloeng sa tumellano sebakeng se bohareng sa ORF45.Re sebelisa immunofluorescence staining, re hlokometse colocalization ea ORF45 le ORF33 kapa USP7 ka bobeli tlas'a maemo a tšoaelitsoeng le lisele tse nang le tšoaetso ea KSHV.Ho feta moo, re hlokometse ho fallisoa ho itšetlehileng ka ORF45 ea karolo ea ORF33 / USP7 ho tloha nucleus ho ea ho cytoplasm.Re fumane hore ORF45 e bakile ho eketseha ha protheine ea ORF33 e ileng ea felisoa haeba sebaka sa ORF33- kapa sa USP7-binding se ORF45 se hlakotsoe.Ho feta moo, ho hlakoloa ha carboxyl terminus e bolokiloeng ea ORF45 ho genome ea KSHV ho fokolitse haholo boemo ba protheine ea ORF33 liseleng tse nang le tšoaetso ea KSHV le ho felisa tlhahiso ea li-virion tsa bana.Ka kopanelo, liphetho tsa rona ha li senole feela likarolo tse ncha tsa ORF45 interactome, empa hape li bontša hore tšebelisano har'a liprotheine tsena ke tsa bohlokoa bakeng sa ho pheta-pheta ha KSHV.KSHV ORF45 ke protheine e sebetsang ka bongata e hlokahalang bakeng sa ho ikatisa ha KSHV lytic, empa mekhoa e nepahetseng eo ORF45 e etsang mesebetsi ea eona ea bohlokoa ha e hlake.Liphuputso tsa rona tse fetileng li senoletse hore liprotheine tsohle tsa ORF45 liseleng li teng ka har'a li-complexes tse boima ba limolek'hule.Ka hona re ne re batla ho tsebahatsa "interome" ea ORF45 ho fana ka leseli mabapi le mesebetsi ea eona nakong ea phetisetso ea lytic.Re sebelisa sehlopha sa li-antibodies tsa monoclonal, re ile ra hlahloba ORF45 interactome liseleng tse nang le tšoaetso ea KSHV.Re khethile balekane ba babeli ba bacha ba tlamang ba ORF45: protheine ea vaerase ORF33 le cellular ubiquitin-specific protease 7 (USP7).Re tsoela pele ho bontša hore tšebelisano pakeng tsa ORF45 le ORF33 ke ea bohlokoa bakeng sa tlhahiso e sebetsang ea likokoana-hloko tsa KSHV, ho fana ka maikutlo a hore tšitiso e lebisitsoeng le tšebelisano ena e ka 'na ea emela leano le lecha la ho thibela ho ikatisa ha KSHV lytic.


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    L-Methionine Cas: 63-68-3 99% White crystalline phofo