L-Histidine Cas: 71-00-1 98.5% Likristale tse tšoeu kapa phofo ea kristale
| Nomoro ea lethathamo | XD90301 |
| Lebitso la Sehlahiswa | L-Histidine |
| CAS | 71-00-1 |
| Foromo ea limolek'hule | C6H9N3O2 |
| Boima ba Molek'hule | 155.15 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29332990 |
Tlhaloso ea Sehlahisoa
| Tlhahlobo | 98.5% mets |
| Ponahalo | Likristale tse tšoeu kapa phofo ea crystalline |
| Kereiti | USP39 |
| Ho potoloha ho itseng | +12,6 ° ho +14,0 ° |
| Boitsebiso | Ho monya ha infrared |
| pH | 7.0 - 8.5 |
| SO4 | <=0.03% |
| Fe | <=30ppm |
| Tahlehelo ka ho Omisa | <=0.2% |
| Masalla a ho Ignition | <=0.1% |
| Cl | <=0.05% |
| Litšepe tse boima (PB) | <=15ppm |
| Metsoako e amanang | Ha ho na ho feta 0.5% ea litšila tsa motho ka mong tse fumanoang;Ha ho fete 2.0% ea litšila tsohle tse fumanoang |
he quadruplex e etsang tatellano ea G-rich e ajoa ka mokhoa o sa tšoaneng ho pholletsa le lefutso la motho.Ho rua ha bona ho batšehetsi ba oncogenic le li-telomere ho hlahisitse thahasello ea ho lebisa tlhokomelo ho G-quadruplex (GQ) bakeng sa phekolo ea anticancer.Mona, re fana ka tlhahlobo ea bongata mabapi le li-conformations le matla a GQ a etsang tatellano e lekantsoeng ke molek'hule e le 'ngoe ea fluorescence.Ho feta moo, re amahanya thepa ena le GQ targeting ligands le G4 resolvase 1 (G4R1) protheine e tlamang.Sephetho sa rona se bontša hore bolelele le tatellano ea loop (karolo eo e seng ea G) e kenya letsoho ho tsamaiseng GQ.Mesaletsa ea nako ea 'nete ea molek'hule e le' ngoe e senola hore matla a ho mena le ona a ipapisitse le sebopeho sa loop.Re bonts'a hore GQ-e tsitsisa limolek'hule tse nyane, N-methyl mesoporphyrin IX (NMM), analog ea eona, NMP le protheine ea G4R1 e tlama ka mokhoa o ikhethileng ho lumellana le GQ e tšoanang.Liphuputso tsa rona li supa ho rarahana ha ho mena ha GQ ho laoloang ke bolelele ba loop le tatellano le hore na khokahano ea GQ e khethollang molek'hule e nyane le propensity e tlamang liprotheine.
