L-Cystine CAS: 56-89-3 99% Likristale tse tšoeu kapa phofo ea kristale
| Nomoro ea lethathamo | XD90322 |
| Lebitso la Sehlahiswa | L-cystine |
| CAS | 56-89-3 |
| Foromo ea limolek'hule | C6H12N2O4S2 |
| Boima ba Molek'hule | 240.30 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29309013 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Likristale tse tšoeu kapa phofo ea crystalline |
| Tlhahlobo | 99% |
| Kereiti | USP32 |
| Ho potoloha ho itseng | -215 ° ho -225 ° |
| Litšepe tse boima | <0.0015% |
| AS | 1.5ppm boholo |
| SO4 | 0.040% boholo |
| Fe | <0.003% |
| Tahlehelo ka ho Omisa | 0.20% boholo |
| Residual on Ignition | 0.10% boholo |
| Cl | 0.10% boholo |
Mehaho ea kristale ea carboxypeptidase T (CpT) e nang le phenylalanine le arginine substrate analogues - benzylsuccinic acid le (2-guanidinoethylmercapto) succinic acid - e laetsoe ke mokhoa oa ho nkela limolek'hule liqetong tsa 1.57 Å le 1.62 profil ea Å ho hlakisa boemo bo itseng ka ho khetheha. ea enzyme.Masala a Conservative a Leu211 le Leu254 (hape a leng teng ka har'a carboxypeptidase A le carboxypeptidase B) a bonts'itsoe e le lintlha tsa sebopeho bakeng sa temoho ea li-substrates tsa hydrophobic, athe Asp263 e ne e le bakeng sa ho amohela li-substrate tse qosoang hantle.Liphetoho tsa li-determinants tsena li fetola profaele ea substrate: mofuta oa CpT Leu211Gln o fumana thepa e kang ea carboxypeptidase B, le mofuta oa CpT oa Asp263Asn khetho ea carboxypeptidase A-joaloka.Pro248-Asp258 loop e sebelisanang le Leu254 le Tyr255 e bontšitsoe e ikarabella bakeng sa temoho ea masala a C-terminal ea substrate.Ho tlama ha substrate sebakeng sa S1 ho lebisa phetohong e tebileng ea ligand-dep ea loop ena, 'me mokhatlo oa ketane oa Leu254 o etsa hore ho be le tlhophiso e ncha ea masala a Glu277 a bohlokoa bakeng sa catalysis.Ena ke temohisiso e ncha mabapi le khetho ea substrate ea metallocarboxypeptidase e bonts'ang bohlokoa ba litšebelisano lipakeng tsa sebaka sa S1 'le setsi sa ho thusa.
