Hoechst 33258 Cas: 23491-45-4 phofo e 'mala o mosehla oa kristale
Nomoro ea lethathamo | XD90536 |
Lebitso la Sehlahiswa | Hoekst 33258 |
CAS | 23491-45-4 |
Foromo ea limolek'hule | C25H24N6O·3(HCl) |
Boima ba Molek'hule | 533.88 |
Lintlha tsa polokelo | -15 ho ea ho -20 ° C |
Khoutu ea Lekhetho e Kopantsoeng | 32129000 |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo ea kristale e 'mala o mosehla |
Tlhahlobo | 99% |
Tšebelisano lipakeng tsa sethethefatsi sa antidiabetic, Metformin le namane thymus DNA (CT-DNA) ho (50mM Tris-HCl) buffer e ile ea ithutoa ke UV-Visible absorption, fluorescence, CD spectroscopy le litekanyo tsa viscosity.Lithutong tsa fluorimetric, enthalpy le entropy ea karabelo lipakeng tsa moriana le CT-DNA li bonts'itse hore karabelo ke exothermic (ΔH = -35.4522 kJ mol(-1); ΔS=-49.9523 J mol(-1)K(-1) )).Lithuto tse tlamang tlholisano li bonts'itse hore moriana o ka lokolla Hoechst 33258 ka botlalo.Motsoako ona o bonts'itse ho monya hyperchromism sebonong sa eona sa UV-Vis le DNA.Nako e lekantsoeng e tlamang, K(b), e fumanoeng lithutong tsa ho monya UV-Vis e ne e le 8.3×10(4)M(-1).Ho feta moo, liphetoho tse hlahang litšoantšong tsa CD ka pel'a sethethefatsi li bontša botsitso ba mofuta oa letsoho le letona oa B oa CT-DNA.Qetellong, litekanyo tsa viscosity li ile tsa senola hore tlamahano e rarahaneng le CT-DNA e ka ba e tlamang ka holim'a metsi, haholo-holo ka lebaka la ho tlama ha groove.Copyright © 2012 Elsevier BV Litokelo tsohle li sirelelitsoe.