Lihlahisoa

Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride ke motsoako oa lik'hemik'hale o ka sebelisoang lefapheng la bongaka le lipatlisiso tsa meriana.E na le sehlopha sa benzyl se kopantsoeng le ts'ebetso ea carbamate, eo hape e amanang le hexahydro-1H-pyrrolizin-7a-ylmethyl moiety.Ho eketsoa ha hydrochloride ho motsoako ho bontša boteng ba ion ea chloride, e ntlafatsang ho qhibiliha ha eona metsing.Motsoako ona o ka ba le lisebelisoa tse 'maloa ka lebaka la likarolo tsa eona tsa sebopeho.Carbamates, ka kakaretso, e tsebahala ka ho bonts'a mesebetsi e fapaneng ea tlhaho, ho kenyelletsa anticonvulsant, anticancer le thepa ea antihypertensive.Ho ba teng ha sehlopha sa benzyl ho benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride e ka fana ka lipophilicity e ntlafetseng, e lumellang hore e tšele lisele tsa cellular habonolo.Sena se ka ba molemo bakeng sa ho fana ka lithethefatsi le ho ntlafatsa bioavailability.Hexahydro-1H-pyrrolizin-7a-ylmethyl moiety, eo hape e tsejoang e le piperidinyl moiety, e atisa ho fumanoa ka metsoako ea bioactive.Li-piperidine li tsejoa ka karolo ea tsona e le li-enzyme inhibitors, li-neurotransmitter modulators, le li-anti-inflammatory agents.Ho kenngoa ha karolo ena ka har'a motsoako ho ka ntlafatsa ts'ebetso ea eona ea likokoana-hloko le bokhoni ba phekolo.Ho sa tsotellehe khaello ea tlhahisoleseding e tobileng mabapi le ts'ebeliso ea liteko kapa meriana ea meriana, litšebeliso tse ka 'nang tsa e-ba teng li ka nahanoa ho latela thepa e tsejoang ea lihlopha tsa eona.Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride e ka hlahlojoa e le moemeli oa lithethefatsi bakeng sa maemo a kang lefu la sethoathoa, mofets'e, khatello ea mali, kapa mafu a neurodegenerative.Ho bohlokoa ho hlokomela hore pele ho ts'ebeliso efe kapa efe e sebetsang kapa lipatlisiso tse tsoelang pele, lipatlisiso le liteko tse kenyellelitsoeng ho kenyelletsa lithuto tsa toxicological, optimization ea k'hemistri ea bongaka, le tlhahlobo khahlano le lipheo tse itseng. e lokela ho etsoa.Sena se tla thusa ho tseba tšireletseho, katleho, le mokhoa o nepahetseng oa ts'ebetso ea benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride, e qetellang e lebisa ho sebelisoa ha eona lefapheng la bongaka.