6-Methoxy-5-nitroquinazoline CAS: 87039-48-3
Nomoro ea lethathamo | XD93472 |
Lebitso la Sehlahiswa | 6-Methoxy-5-nitroquinazoline |
CAS | 87039-48-3 |
Foromo ea molek'hulela | C9H7N3O3 |
Boima ba Molek'hule | 205.17 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
6-Methoxy-5-nitroquinazoline ke motsoako oa lik'hemik'hale o nang le lisebelisoa tse sa tšoaneng tšimong ea organic synthesis le lipatlisiso tsa meriana.Sebopeho sa eona sa limolek'hule se na le lesale la quinazoline le sehlopha sa methoxy sebakeng sa 6 le sehlopha sa nitro sebakeng sa 5. E 'ngoe ea litšebeliso tse ka sehloohong tsa 6-methoxy-5-nitroquinazoline ke tsoelo-pele le motsoako oa metsoako e mecha ea meriana.The scaffold quinazoline e teng ka har'a motsoako ona ke mokhoa o tloaelehileng oa sebopeho o fumanoang limolek'hule tse ngata tsa bioactive.Bafuputsi ba ka sebelisa 6-methoxy-5-nitroquinazoline e le ntho e qalang ho hlahisa li-analogues kapa lihlahisoa tse nang le thepa e ntlafetseng ea meriana.Ka ho fetola li-substituents tsa lesale la quinazoline, bafuputsi ba ka ntlafatsa khetho ea motsoako, ho kopana ha li-receptor, le ho sebetsa hantle ha phekolo.Ho feta moo, 6-methoxy-5-nitroquinazoline e ka sebelisoa e le motsoako oa bohlokoa oa lisebelisoa ho baeloji le lipatlisiso tsa lik'hemik'hale tsa meriana.E ka sebetsa e le ligand kapa probe ho ithuta kamano e tlamang le khetho ea li-receptor tse itseng kapa li-enzyme.Litšebelisano tsa lik'hemik'hale tsena le lipakane tsa likokoana-hloko li ka fana ka lintlha tsa bohlokoa ka mekhoa ea motheo ea mafu a sa tšoaneng le ho thusa ho nts'etsopele ea mekhoa ea phekolo e lebisitsoeng.Ho feta moo, 6-methoxy-5-nitroquinazoline e ka kenngoa lilaebraring tsa metsoako e hlahlojoang khahlanong le lipakane tse khethehileng tsa lithethefatsi. mananeo a ho sibolla.Tlhahlobo e phahameng ea lilaebrari tsena tsa metsoako e thusa ho tseba metsoako e ka bang teng ea loto kapa batho ba sebelisang lithethefatsi ba nang le mesebetsi e lakatsehang ea meriana.E boetse e thusa ho hlahlobisisa mekhoa e mecha ea phekolo ka ho senola lipakane tse ncha tsa likokoana-hloko.Ho phaella moo, 6-methoxy-5-nitroquinazoline e ka fumana likopo ho li-lab tsa lipatlisiso tsa thuto le tsa indasteri tse ithutang liketsahalo tse sa tšoaneng tsa likokoana-hloko.Sebopeho sa eona se ikhethang le ts'ebetso ea ts'ebetso e etsa hore e be sebaka sa ho haha tse ngata bakeng sa motsoako oa limolek'hule tse rarahaneng.Bafuputsi ba ka e sebelisa e le ntho ea ho qala kapa ea bohareng ho haha lilaebrari tsa lik'hemik'hale tse sa tšoaneng kapa ho lokisa thepa ea limolek'hule mererong ea ho kopanya e amanang le lik'hemik'hale tsa meriana kapa likarolo tse ling tsa lipatlisiso tsa saense. seabo ho organic synthesis le lipatlisiso tsa meriana.Sekhafo sa eona sa quinazoline le lik'hemik'hale tse fapa-fapaneng tseo e kopanang le tsona li etsa hore e be ntho ea bohlokoa ea ho qala bakeng sa nts'etsopele ea metsoako ea bioactive.Ho feta moo, ho feto-fetoha ha eona joalo ka motsoako oa lisebelisoa ho etsa hore ho be le lipatlisiso tse qaqileng mabapi le mekhoa ea ts'ebetso ea lithethefatsi le ho sibolloa ha limolek'hule tse ka bang teng tsa kalafo.Lintho tse ikhethang tsa 6-methoxy-5-nitroquinazoline li etsa hore e be letlotlo la bohlokoa lefapheng la lik'hemik'hale tsa meriana, ho sibolloa ha lithethefatsi, le lipatlisiso tsa likokoana-hloko.