5,5-Dithiobis(2-nitrobenzoic acid) Cas: 69-78-3 99% Lehlaka le phofshoana le mosehla
| Nomoro ea lethathamo | XD90158 |
| Lebitso la Sehlahiswa | 5,5-Dithiobis(2-nitrobenzoic acid) |
| CAS | 69-78-3 |
| Foromo ea limolek'hule | C14H8N2O8S2 |
| Boima ba Molek'hule | 396.35 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29309098 |
Tlhaloso ea Sehlahisoa
| Nomoro ea lethathamo | XD90158 |
| Lebitso la Sehlahiswa | 5,5-Dithiobis(2-nitrobenzoic acid) |
| CAS | 69-78-3 |
| Foromo ea limolek'hule | C14H8N2O8S2 |
| Boima ba Molek'hule | 396.35 |
| Lintlha tsa polokelo | Ambient |
| Khoutu ea Lekhetho e Kopantsoeng | 29309098 |
Ho thehoa ha Acyl-CoA ho qala metabolism ea mafura a cellular.Acyl-CoAs e hlahisoa ke ho kopana ha mafura a mafura ho Coenzyme A e kentsoeng ke lelapa le leholo la acyl-CoA synthetases (ACS).Ka lehlakoreng le leng, acyl-CoAs e ka hydrolyzed ke lelapa la acyl-CoA thioesterases (ACOT).Mona, re entse qeto ea taolo ea mongolo oa li-enzyme tsohle tsa ACS le ACOT ho pholletsa le lisele le ho arabela ho ferekanngoa ha metabolism.Re fumana mekhoa ea taolo e hokahaneng ka hare le lipakeng tsa malapa ana a liphatsa tsa lefutso hammoho le taolo e ikhethileng e etsahalang ka mokhoa o itšetlehileng ka 'mele le fisioloji.Ka lebaka la liphetoho tse bonoang ho ketane e telele ea ACOT mRNA le bongata ba liprotheine sebeteng le liseleng tsa adipose, re ile ra fumana sephetho sa ts'ebetso e ntseng e eketseha ea cytosolic long-chain thioesterase metabolism ho mafura a acid ka har'a lisele tsena ka ho hlahisa litoeba tsa transgenic overexpressing hyperactive mutant ea Acot7 sebete kapa lisele tsa adipose.Ts'ebetso e habeli ea cytosolic acyl-CoA thioesterase e hlolehile ho sireletsa mic e ho botenya bo bakoang ke lijo, sebete se mafura kapa ho hanyetsa insulin, leha ho le joalo, ho fetella ha Acot7 ho adipocyte ho entseng hore litoeba li se mamelle serame.Hammoho, lintlha tsena li fana ka maikutlo a mekhoa e fapaneng ea taolo ea li-enzyme tsa ACS le ACOT le hore li-enzyme tsena li sebetsa ka mokhoa o kopanetsoeng ho laola metabolism ea mafura a mafura ka mokhoa o itšetlehileng ka lisele.
