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Lihlahisoa

5-Nitro-1,10-phenanthroline CAS:4199-88-6 Leseli le mosehla ho isa ho kristale e sootho

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD90385
CAS: 4199-88-6
Foromo ea molek'hule: C12H7N3O2
Boima ba Molek'hule: 225.21
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana: 1g USD20
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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD90385
Lebitso la Sehlahiswa 5-Nitro-1,10-phenanthroline
CAS 4199-88-6
Foromo ea limolek'hule C12H7N3O2
Boima ba Molek'hule 225.21

 

Tlhaloso ea Sehlahisoa

Melting Point 200 - 203 °C
Tlhahlobo 99%
Ponahalo kristale e 'mala o mosehla ho isa ho sootho

 

Ho entsoe li-metallointercalators tse leshome le metso e mehlano tse thehiloeng ho platinum(II) tse sebelisang li-ligands tsa 1,10-phenanthroline (phen), ho kenyeletsoa 5-chloro-1,10-phenanthroline (5-Cl-phen), 5-methyl-1,10- phenanthroline (5-CH3-phen), 5-amino-1,10-phenanthroline (5-NH2-phen), 5-nitro-1,10-phenanthroline (5-NO2-phen) le dipyrido[3,2-d :2',3'-f]quinoxaline (dpq), and achiral ethylenediamine (en) and the chiral ancillary ligands 1S,2S-diaminocyclohexane (S,S-dach) le 1R,2R-diaminocyclohexane (R,R-dach) .Cytotoxicity ea bona ho L1210 murine leukemia cell line e ne e ikemiselitse ho sebelisa liteko tsa thibelo ea kholo.Metsoako ea tšepe ea cytotoxic ka ho fetisisa ke e nang le S,S-dach ancillary ligands le 5-CH3-phen intercalating ligands.Metallointercalator e le 'ngoe [Pt(5-CH3-phen)(S,S-dach)]Cl2 (5MESS), e bonts'a keketseho ea 5-10 ea cytotoxicity ha e bapisoa le moemeli oa kliniki cisplatin.Ho tsoa litekong tse tlamang tsa DNA ho bonahala ho se na phapang e kholo lipakeng tsa li-complexes tsa tšepe, ho bonts'a hore ha ho na DNA e tlamang kamano kapa mokhoa oa ho tlama / DNA adduct e entsoeng ke eona feela e khethollang cytotoxicity ea lelapa lena la platinum(II)-based. metallointercalators.

 


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    5-Nitro-1,10-phenanthroline CAS:4199-88-6 Leseli le mosehla ho isa ho kristale e sootho