Lihlahisoa

4,5,6,7-Tetrahydrothieno[3,2,c]pyridine hydrochloride, e tsejoang hape e le THP hydrochloride, ke motsoako oa lik'hemik'hale o nang le foromo ea molek'hule C8H11NS·HCl.Ke phofo e tšoeu ea kristale e atisang ho sebelisoa ho organic synthesis le lipatlisiso tsa meriana.E 'ngoe ea lisebelisoa tse ka sehloohong tsa 4,5,6,7-Tetrahydrothieno[3,2,c]pyridine hydrochloride e le mohaho o nang le mekhoa e mengata ea ho haha. mefuta e fapaneng ea metsoako ea organic.E na le motsoako oa thienopyridine, o fanang ka mohaho o ikhethang bakeng sa kaho ea limolek'hule tse rarahaneng.The thienopyridine motif e ka khethoa ka mokhoa o ikhethileng, e lumellang hore ho kenyelletsoe lihlopha tse sa tšoaneng tse sebetsang ho fetola thepa le ts'ebetsong ea metsoako e hlahisoang. ea bohlokoa lipakeng ho kopanngoeng ha meriana e mengata.Ka mohlala, e ka sebelisoa ha ho etsoa litlhare tse thibelang ho ferekana kelellong, tse kang clozapine le olanzapine, tse atisang ho sebelisoa ho alafa lefu la schizophrenia le lefu la ho ferekana kelellong.Motsoako ona o ka boela oa sebelisoa ha ho etsoa metsoako e meng ea phekolo, ho akarelletsa li-analgesics, anti-inflammatories, le lithethefatsi tse thibelang likokoana-hloko. bakeng sa tlhahiso ea limolek'hule tse sebetsang ka biologically.Ka ho fetola li-substituents tsa lesale la thienopyridine, bo-rasaense ba ka hlophisa metsoako e hlahisoang hore e shebane le litsela tse itseng tsa likokoana-hloko kapa li-receptors.Sebopeho sena se feto-fetohang se etsa hore e be sesebelisoa sa bohlokoa ho sibolloeng le ho nts'etsopele ea lithethefatsi.Ntho e 'ngoe ea bohlokoa ea 4,5,6,7-Tetrahydrothieno[3,2,c]pyridine hydrochloride ke bokhoni ba eona ba ho sebetsa e le sehlopha se sireletsang lihlopha tse sebetsang hantle nakong ea karabelo ea lik'hemik'hale.Sehlopha sa THP se ka hlahisoa habonolo mme ka mor'a moo sa tlosoa tlas'a maemo a bonolo, ho lumella ts'ireletso ea lihlopha tse sebetsang tse tlokotsing ha maikutlo a mang a ntse a etsahala.Ho bohlokoa ho hlokomela hore tšebeliso e khethehileng ea 4,5,6,7-Tetrahydrothieno[3,2,c]pyridine hydrochloride e fapana ho ea ka seo u se batlang. molek'hule ea sepheo le maemo a karabelo.Litsebi tsa lik'hemik'hale li lokela ho ba hlokolosi 'me li latele mekhoa e nepahetseng ea tšireletso ha li sebetsana le ho sebelisa motsoako ona.Ho feta moo, litataiso tse thata tsa taolo li lokela ho lateloa ho netefatsa tšebeliso e nepahetseng le e nang le boikarabelo ea motsoako ona lipatlisisong tsa meriana.