Lihlahisoa

4''-Propyl-3-fluorobiphenyl-4-boronic acid, eo hape e tsejoang e le (4-propyl-3-fluorophenyl)boronic acid, ke motsoako oa lik'hemik'hale o fumaneng ts'ebeliso ea bohlokoa mafapheng a fapaneng, ho kenyelletsa le organic synthesis, mahlale a thepa, le lipatlisiso tsa meriana.E 'ngoe ea lits'ebetso tsa mantlha tsa 4''-Propyl-3-fluorobiphenyl-4-boronic acid ke phetohong ea tšepe-catalyzed coupling reactions.Motsoako ona o ka sebetsa e le mohaho oa mohaho oa boronic acid, o lumellang ho thehoa ha carbon-carbon kapa carbon-heteroatom bonds.Mohlala, e ka sebelisoa ho Suzuki-Miyaura cross-coupling reactions, moo e sebetsanang le aryl kapa vinyl halides tlasa palladium catalysis ho hlahisa metsoako ea biaryl.Liphetoho tsena tse kopanyang li sebelisoa haholo ha ho etsoa limolek'hule tse rarahaneng tsa lintho tse phelang, ho kenyeletsoa meriana, lik'hemik'hale le lisebelisoa. e fana ka menyetla e ikhethang bakeng sa nts'etsopele ea lisebelisoa tse sebetsang.Phatlalatso ea fluorine e ka ba le tšusumetso e kholo ho thepa ea physicochemical ea molek'hule, joalo ka kabo ea eona ea elektroniki le hydrophobicity.Lintho tsena li etsa li-derivatives tsa 4''-Propyl-3-fluorobiphenyl-4-boronic acid tse sebetsang lits'ebetsong tse fapaneng, tse kang likristale tsa metsi, OLED (organic light-emitting diodes), le lisebelisoa tse ling tsa elektronike. Ho feta moo, sehlopha sa propyl sebopeho sa 4''-Propyl-3-fluorobiphenyl-4-boronic acid se lumella ho tsoa habonolo, ho fana ka monyetla oa ho fumana mefuta e mengata ea lihlahisoa tse sebetsang.Ho feto-fetoha ha maemo ho etsa hore ho be le metsoako e fapaneng e nang le thepa le mesebetsi e hlophisitsoeng.Lintho tsena tse nkiloeng li ka ntlafatsoa hape kapa tsa kenyelletsoa ho meralo e meholoanyane ea limolek'hule ho theha limolek'hule tse rarahaneng, limolek'hule tsa bioactive, le lisebelisoa tse tsoetseng pele. batho ba ka khonang ho sibolla lithethefatsi.Metsoako e nang le fluorinated hangata e bonts'a botsitso bo ntlafetseng ba metabolism, ho eketseha ha lipophilicity, le ts'ebetso e fetotsoeng ea likokoana-hloko ha e bapisoa le balekane ba bona ba se nang fluorinated.Ka hona, ho kenngoa ha athomo ea fluorine ka har'a limolek'hule tse sebetsang ka biologically ho ka ntlafatsa thepa ea bona ea meriana, joalo ka potency le selectivity. , saense ea thepa, le lipatlisiso tsa meriana.Bokhoni ba eona ba ho kenya letsoho phetolong ea phetoho ea tšepe-catalyzed coupling, thepa e ikhethang e amanang le sebaka sa fluorine, le monyetla oa ho tsoa ho eona li e etsa sesebelisoa sa bohlokoa bakeng sa tlhahiso ea limolek'hule tse rarahaneng tsa organic, lisebelisoa tse sebetsang, le batho ba ka bang teng ho sebelisa lithethefatsi.