(2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy -2H-pyran-3,4,5-triol CAS: 1279691-36-9
| Nomoro ea lethathamo | XD93372 |
| Lebitso la Sehlahiswa | (2S,3R,4S,5S,6R)-2-(3-(4-(S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy -2H-pyran-3,4,5-triol |
| CAS | 1279691-36-9 |
| Foromo ea molek'hulela | C24H29ClO8 |
| Boima ba Molek'hule | 480.94 |
| Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Assay | 99% mets |
Motsoako (2S,3R,4S,5S,6R) -2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2 -methoxy-2H-pyran-3,4,5-triol ke molek'hule e rarahaneng e nang le lisebelisoa tse ka sebelisoang likarolong tse sa tšoaneng, ho akarelletsa le lik'hemik'hale tsa meriana le tsa meriana. ka lesale le leng la pyran.Ho ba teng ha li-stereocenters tse ngata ka sebopeho sa eona ho etsa hore e be molek'hule ea chiral, e bolelang hore e teng ka mefuta e 'meli ea enantiomeric e ka bang le mesebetsi e fapaneng ea likokoana-hloko.E 'ngoe ea ts'ebeliso ea motsoako ona ke ho sibolloa ha lithethefatsi le nts'etsopele.Likarolo tsa sebopeho sa molek'hule, joalo ka lihlopha tsa benzyl le chlorophenyl, li kopantsoe le boteng ba lihlopha tse ngata tsa hydroxyl, li fana ka maikutlo a hore e ka bonts'a ts'ebetso ea tlhaho.Litsebi tsa lik'hemik'hale tsa meriana li ka hlahloba bokhoni ba motsoako e le motsoako o ka sehloohong bakeng sa nts'etsopele ea lithethefatsi tse ncha, haholo-holo tse lebisang maloetse a amanang le metabolism ea lik'habohaedreite. Ho ba teng ha sehlopha sa (S) -tetrahydrofuran-3-yloxy ho fana ka maikutlo a hore motsoako o ka ba le bokhoni ba ho sebelisana. ka li-receptor kapa li-enzyme tse amehang ho metabolism ea carbohydrate kapa litselana tsa matšoao.Bafuputsi ba ka batlisisa bokhoni ba eona e le inhibitor kapa modulator ea li-enzyme kapa li-receptor tse itseng tse amehang lits'ebetsong tsena.Ho phaella moo, ho rarahana ha sebopeho sa motsoako ho ka 'na ha etsa hore e be mokhethoa ea loketseng bakeng sa ho ntlafatsa k'hemistri ea meriana ka liphetoho tsa meralo.Ho feta moo, scaffold ea motsoako oa pyranopyran e na le lihlopha tse ngata tsa hydroxyl, e leng lihlopha tsa bohlokoa tse sebetsang ho moralo oa lithethefatsi.Lihlopha tsa Hydroxyl li ka kenya letsoho likamanong tsa hydrogen bonding, tse susumetsang ho qhibiliha ha motsoako, botsitso le thepa ea pharmacokinetic.Litsebi tsa meriana li ka sebelisa lihlopha tsena ho ntlafatsa potency ea motsoako, selectivity, le thepa e meng ea pharmacological. The compound's structural complexity e boetse e fana ka maikutlo a ts'ebeliso e ka 'nang ea e-ba teng ho saense ea thepa le organic synthesis.Tlhophiso ea eona e ikhethang ea lihlopha tse sebetsang e ka sebelisoa bakeng sa ho kopanya li-organic compounds tse ncha tse nang le thepa kapa mesebetsi e itseng.Ho phaella moo, motsoako o ka 'na oa sebetsa e le qalo ea tlhahiso ea lisebelisoa tse ncha, tse kang li-polymers kapa li-supramolecular structures, tse nang le lisebelisoa tse ka sebelisoang liindastering tse sa tšoaneng.Qetellong, motsoako (2S,3R,4S,5S,6R) -2- (3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol possesss structural likarolo tse e etsang hore e be molemo ho k'hemistri ea meriana le ea bongaka, mahlale a lisebelisoa, le organic synthesis.Sebopeho sa eona se rarahaneng le lihlopha tse fapaneng tse sebetsang li fana ka menyetla ea ho batlisisa ho sibolloa ha lithethefatsi, ho feto-fetoha ha enzyme, nts'etsopele ea thepa le libaka tse ling tsa lipatlisiso.
