Lihlahisoa

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) ke motsoako oa lik'hemik'hale o tsejoang ka likopo tsa oona ho organic synthesis, haholo-holo tšimong ea lik'hemik'hale tsa lik'hemik'hale.Ke ntho e tsoang ho D-glucose, e leng tsoekere ea tlhaho, 'me e na le thepa e ikhethang e etsang hore e be molemo mekhoeng e sa tšoaneng ea lik'hemik'hale.E 'ngoe ea litšebeliso tsa mantlha tsa TMS-D-glucose lactone ke sehlopha se sireletsang lik'hemik'hale tsa lik'hemik'hale.Li-carbohydrate, ho kenyelletsa le tsoekere, li ka ba le lihlopha tse ngata tsa hydroxyl, tse ka sebetsanang le li-reagents tse ling kapa tsa etsa liphetoho tse sa batleheng nakong ea synthesis.Ka ho sireletsa lihlopha tse khethehileng tsa hydroxyl tse sebelisang TMS-D-glucose lactone, litsebi tsa lik'hemik'hale li ka laola liphello tsa karabelo le ho laola mekhoa ea lik'habohaedreite ka katleho.Ka mor'a hore likarabo tse lakatsehang li phethoe, lihlopha tse sireletsang li ka tlosoa habonolo, li senola sehlahisoa se lakatsehang.TMS-D-glucose lactone e boetse e fumana likopo e le karolo e bohareng ea motsoako oa lik'habohaedreite tse rarahaneng haholoanyane.Ka ho khetha ka ho khetha lihlopha tsa hydroxyl tsa TMS-D-glucose lactone, litsebi tsa lik'hemik'hale li ka hlahisa lihlopha tse ngata tse sebetsang kapa tse ling tse kenang ka har'a molek'hule ea lik'habohaedreite.Sena se lumella ho theoa ha metsoako e fapaneng ea lik'habohaedreite tse nang le ts'ebeliso e ka bang teng ho tsa meriana, litlolo, le mahlale a thepa. Ho feta moo, TMS-D-glucose lactone e sebelisoa ha ho etsoa bafani ba glycosyl bakeng sa karabelo ea glycosylation.Glycosylation ke mohato oa bohlokoa ho thehoeng ha litlamo tsa glycosidic, tse bohlokoa bakeng sa kaho ea lik'habohaedreite le glycoconjugates.TMS-D-glucose lactone e ka fetoloa bafani ba glycosyl, e sebetsang e le li-intermediate tse sebetsang ka har'a glycosylation reactions, e leng ho nolofalletsang ho khomarela lik'habohaedreite ho limolek'hule tse ling.Ho feta moo, TMS-D-glucose lactone e sebelisoa ho hlahisa li-polymers tsa lik'habohaedreite.Ka ho beha TMS-D-glucose lactone ho karabelo ea polymerization, litsebi tsa k'hemistri li ka etsa liketane tsa polymer kapa marang-rang a nang le mokokotlo oa lik'habohaedreite.Li-polymer tsena tsa lik'habohaedreite li ka ba le thepa e ikhethang 'me li ka fumana lits'ebetso libakeng tse kang litsamaiso tsa phepelo ea lithethefatsi, bioengineering, le biomaterials.Ke habohlokoa ho hlokomela hore TMS-D-glucose lactone e lokela ho sebetsoa ka hloko ka lebaka la mongobo oa eona le maikutlo a moea.Ka tloaelo e bolokoa le ho sebetsoa ka tlas'a nitrogen kapa argon atmospheres ho thibela ho senyeha. k'hemistri ea lik'habohaedreite.Lisebelisoa tsa eona tse ka sehloohong li kenyelletsa ho sireletsa k'hemistri ea sehlopha, motsoako oa bohareng, sebopeho sa bafani ba glycosyl, le tlhahiso ea li-polymers tsa lik'habohaedreite.Ka ho sebelisa TMS-D-glucose lactone lits'ebetsong tsena, litsebi tsa k'hemistri li ka fihlela taolo e betere holim'a karabelo ea lik'habohaedreite le ho theha mefuta e fapaneng e tsoang ho lik'habohaedreite ka ts'ebeliso e ka bang teng mafapheng a fapaneng.