Lihlahisoa

2-Piperazinecarboxylic acid dihydrochloride, e tsejoang hape e le piperazine dihydrochloride, ke motsoako oa lik'hemik'hale o sebelisoang lits'ebetsong tse fapaneng ho pholletsa le liindasteri.E na le mefuta e mengata ea tšebeliso ea meriana, organic synthesis, le lipatlisiso tsa lik'hemik'hale tsa likokoana-hloko. Lefapheng la meriana, piperazine dihydrochloride e sebetsa e le ntho e qalang ho kopanngoa ha lithethefatsi tse 'maloa.Tšebeliso ea eona e ka sehloohong ke ho hlahisa meriana ea anthelmintic e sebelisoang ho phekola mafu a likokoana-hloko, haholo-holo ho loantša liboko tsa mala.Piperazine dihydrochloride e atleha ho holofatsa tsamaiso ea methapo ea likokoana-hloko tsena, e lebisang ho lelekoa ha tsona 'meleng.Motsoako ona o atisa ho sebelisoa tlhahisong ea lithethefatsi tsa anthelmintic tse kang Mebendazole le Praziquantel.Ho feta moo, piperazine dihydrochloride e sebelisoa haholo litlhophisong tsa laboratori le indasteri bakeng sa ho kopanya metsoako ea lintho tse phelang.E sebetsa e le setsi sa ho haha ​​​​se nang le mekhoa e mengata ho etsa lihlahisoa tse fapaneng tsa lik'hemik'hale.Bokhoni ba ho fetola sebopeho sa eona bo nolofalletsa nts'etsopele ea metsoako e mecha e nang le thepa e khethehileng, e etsa hore e be sesebelisoa sa bohlokoa tšimong ea organic synthesis.Bafuputsi ba sebelisa piperazine dihydrochloride ho etsa limolek'hule tsa tlhaho bakeng sa lithuto tsa lik'hemik'hale tsa meriana, ho ithuta lithethefatsi tse ncha, le ho hlahloba lipakane tse ka 'nang tsa e-ba teng tsa phekolo.E sebelisoa ho lokisa litharollo tsa buffer bakeng sa lits'ebetso tsa liteko tse kenyelletsang li-enzyme le liprotheine.Litšobotsi tsa ho qhibiliha le botsitso ba motsoako li etsa hore e lokele ho sebelisoa lits'ebetsong tsena.Ho ba teng ha eona ho thusa ho boloka tikoloho e tsitsitseng ea pH, e leng ea bohlokoa bakeng sa ho boloka ts'ebetso e nepahetseng ea enzyme le ho netefatsa liphello tse nepahetseng tsa liteko.Ho bohlokoa ho sebetsana le piperazine dihydrochloride ka tlhokomelo le ho latela tataiso ea tšireletso.Motsoako ona o ka halefisa letlalo, mahlo le tsamaiso ea ho hema.Ka hona, lisebelisoa tse nepahetseng tsa tšireletso, tse kang liatlana le likhalase, li lokela ho sebelisoa nakong ea ho tšoaroa ha eona.E boetse e lokela ho bolokoa sebakeng se omeletseng le se nang le moea o motlakase hole le lintho tse sa lumellaneng.E sebetsa e le sesebelisoa sa ho qala tlhahiso ea lithethefatsi tsa anthelmintic mme e fumana ts'ebeliso e kholo ho organic synthesis bakeng sa ho theha lihlahisoa tse fapaneng tsa lik'hemik'hale.Ho feta moo, karolo ea eona lipatlisisong tsa biochemical e etsa hore e be ea bohlokoa ho lokiseng litharollo tsa buffer.Ho latela mehato e nepahetseng ea ts'ireletso ho bohlokoa ha o sebetsa le piperazine dihydrochloride.