Lihlahisoa

2-Hydroxyphenylboronic acid, eo hape e tsejoang e le o-hydroxyphenylboronic acid, ke motsoako oa lintho tse phelang tse ngata o sebelisoang haholo likarolong tse fapaneng, ho kenyelletsa le organic synthesis, thepa ea mahlale, le chemistry ea meriana. reagent ea bohlokoa bakeng sa ho thehoa ha carbon-carbon bond.Li-acid tsa boronic, tse kang 2-Hydroxyphenylboronic acid, li arabela habonolo ka li-nucleophiles, tse kang joala kapa li-amine, ho etsa boronate ester.Li-ester tsena tsa boronate li ba le liphetoho tse latelang, tse kang Suzuki-Miyaura cross-coupling reactions, e leng se lumellang kaho ea limolek'hule tse rarahaneng.Reactivity ena e feto-fetohang e etsa hore 2-Hydroxyphenylboronic acid e be motheo oa bohlokoa oa ho haha ​​​​motsoako oa meriana, agrochemicals, le lik'hemik'hale tse ntle. Ntle le ho thehoa ha carbon-carbon bond, 2-Hydroxyphenylboronic acid e ka ba le mekhoa e fapaneng ea ho hlahisa lihlopha tse ling tse sebetsang.Mohlala, e ka tšeloa oxidized ho theha quinones kapa aryl radicals, e ka sebetsoang le ho feta ho hlahisa scaffolds tsa lik'hemik'hale tse fapaneng.Liphetoho tsena li ntlafatsa tšebeliso ea maiketsetso ea 2-Hydroxyphenylboronic acid le ho etsa hore ho thehoe limolek'hule tse rarahaneng ka mokhoa o hlophisitsoeng.Kopo e 'ngoe ea bohlokoa ea 2-Hydroxyphenylboronic acid e itšetlehile ka saense ea thepa.Sehlopha sa hydroxy se teng ka har'a molek'hule se lumella litšebelisano tse matla tsa hydrogen bonding, e leng se etsang hore e be moaho oa bohlokoa bakeng sa ho rala likopano tsa supramolecular kapa lisebelisoa tse sebetsang.Bokhoni ba ho theha li-hydrogen bond bo thusa ho ikopanya ha 2-Hydroxyphenylboronic acid hore e be li-nanostructures tse hlalositsoeng hantle kapa ho fetoloa ha libaka ho fana ka thepa e lakatsehang, e kang ho ntlafatsa hydrophilicity kapa biocompatibility.Ho feta moo, 2-Hydroxyphenylboronic acid e fumane tlhokomelo ho k'hemistri ea meriana ka lebaka la bokhoni ba eona e le motsoako oa bioactive.Boronic acid moiety e ka khetha ho sebelisana le diols kapa lihlopha tse sebetsang tsa boronate ester-sensitive ho lipakane tsa likokoana-hloko, e leng se etsang hore e be karolo ea bohlokoa moralong oa li-enzyme inhibitors kapa li-receptor ligands.Mokhoa ona o thehiloeng ho boronate o bontšitse tšepiso ea tsoelo-pele ea phekolo ea mafu a sa tšoaneng, ho akarelletsa le kankere, lefu la tsoekere le ho ruruha.Ka kakaretso, 2-Hydroxyphenylboronic acid ke motsoako o nang le mekhoa e mengata e nang le mekhoa e mengata e sebelisoang haholo ho organic synthesis, thepa ea saense le k'hemistri ea meriana.Reactivity ea eona ha ho etsoa bond ea carbon-carbon bond, bokhoni ba ho hlahisa lihlopha tse ling tse sebetsang, le bokhoni ba ho ba motsoako oa bioactive ho etsa hore e be sesebelisoa sa bohlokoa ho bafuputsi lithutong tse fapaneng tsa saense.