Urease CAS:9002-13-5
Nomoro ea lethathamo | XD90388 |
Lebitso la Sehlahiswa | Urease |
CAS | 9002-13-5 |
Foromo ea limolek'hule | N/A |
Boima ba Molek'hule | - |
Lintlha tsa polokelo | 2 ho isa ho 8 °C |
Khoutu ea Lekhetho e Kopantsoeng | 35079090 |
Tlhaloso ea Sehlahisoa
Tlhahlobo | 99% |
Ponahalo | Phofo e tšoeu |
Nickel ke ntho e khethollang kokoana-hloko bakeng sa kokoana-hloko ea gastric Helicobacter pylori.Ka sebele, H. pylori e na le li-enzyme tse peli tsa nickel tse bohlokoa bakeng sa vivo colonization, [NiFe] hydrogenase le urease, ntho e ngata ea virulence e nang le li-ion tsa 24 tsa nickel ka mokhoa o sebetsang.Ka lebaka la li-enzyme tsena tse peli, ho phela ha H. pylori ho itšetlehile ka phepelo ea bohlokoa ea nickel, e leng ho bolelang hore ho na le taolo e tiileng ea kabo le polokelo ea eona.Tlhahlobisong ena, re tla hlahisa litsela tsa ts'ebetso ea li-enzyme tsa nickel hammoho le mekhoa ea pele e fumanoang H. pylori bakeng sa ho nka, ho rekisa le ho ajoa ha nickel pakeng tsa li-enzyme tse peli.Tsena li kenyelletsa (i) tsamaiso ea ka ntle ea nickel ea ka ntle, sepalangoang se itšetlehileng ka FrpB4 TonB, (ii) li-protein complexes tse fetang le marang-rang a amanang le khoebo ea nickel le kabo pakeng tsa urease le hydrogenase le, (iii) Helicobacter tse tlamang nickel protheine. tse amehang polokelong ea nickel mme li ka bapala karolo ea metallo-chaperones.Qetellong, re tla tšohla se boleloang ke balekane ba khoebo ea nickel ka virulence le ho ba sisinya e le lipheo tse ncha tsa phekolo bakeng sa phekolo khahlanong le tšoaetso ea H. pylori.