Lihlahisoa

Trifluoromethanesulfonic anhydride, eo hangata e tsejoang e le triflic anhydride kapa Tf2O, ke reagent e feto-fetohang e sebelisoang haholo ho organic synthesis, haholo lefapheng la k'hemistri ea maiketsetso.Ke motsoako o sebetsang haholo o sebeletsang merero e mengata ka lebaka la acidity e matla le bokhoni ba ho etsa liphetoho tse fapaneng tsa lik'hemik'hale. E 'ngoe ea ts'ebeliso ea mantlha ea triflic anhydride ke e le ntho e thibelang metsi.E sebetsana ka matla le lino tse tahang, e li fetola li-ether tsa tsona tse lumellanang.Karabelo ena, e tsejoang ka hore ke Williamson ether synthesis, hangata e sebelisoa maemong a laboratori le lits'ebetsong tsa indasteri ho theha limolek'hule tse rarahaneng tsa manyolo.Triflic anhydride e thusa haholo bakeng sa ho fetola li-alcohol tse thibetsoeng, tse ka 'nang tsa se ke tsa itšoara habonolo ha li kopana le li-reagents tse ling, ho li etsa li-ethers ka katleho.E ka sebelisoa ho sireletsa lihlopha tse sebetsang hantle, tse kang joala le li-amine, ka ho etsa li-triflates tse tsitsitseng.Li-triflates tsena li ka sireletsoa ka mokhoa o ikhethileng tlas'a maemo a nepahetseng ho nchafatsa lihlopha tse lakatsehang tsa ts'ebetso.Leano lena ke la bohlokoa ka ho khetheha molemong oa ho kopanya mehato e mengata, moo tšireletso le ts'ireletso ea lihlopha tse sebetsang li hlokahalang ho finyella liketso tse lakatsehang ka mokhoa o ikhethileng.Triflic anhydride e boetse e fumana ts'ebeliso e le mokelikeli le motšehetsi liketsong tse sa tšoaneng.Asiti ea eona e phahameng, e tsoang ho trifluoromethanesulfonic acid eo e e hlahisang ka pel'a metsi, e thusa karabelo ea acid-catalyzed.E ka khothalletsa liphetoho tse fapa-fapaneng tse kang li-esterifications, acylations, le rearrangements, tse nolofalletsang ho kopanya limolek'hule tse rarahaneng.Ho feta moo, triflic anhydride e sebelisoa e le electrophile e matla ka liketso tse fapaneng.E ka sebetsana le li-nucleophiles ho hlahisa lihlopha tsa triflyl (CF3SO2), tse sebetsang ka mokhoa o fapaneng ho k'hemistri ea maiketsetso.Lihlopha tsa Triflyl li sebetsa e le lihlopha tse ntle tsa ho tlohela, tse nolofalletsang maikutlo a latelang a kang nucleophilic substitutions kapa rearrangements.Ho sa tsotellehe thuso ea eona, triflic anhydride e tlameha ho sebetsoa ka hloko ka lebaka la tlhaho ea eona e senyang haholo le ts'ebetso e ka bang teng hape.Ho lokela hore ho nkoe mehato e loketseng ea tšireletso, ho kopanyelletsa le ho sebelisa liaparo tse loketseng tsa tšireletso, liatlana le liaparo tsa mahlo, hammoho le ho sebetsa sebakeng se nang le moea o motle.Ho phaella moo, ka lebaka la tlhaho ea eona ea ho senya, ho kgothaletswa ho sebetsana le triflic anhydride tlas'a moea o sa tsitsang. lihlopha, li-catalyst, motšehetsi, le motlakase oa motlakase.Ho feto-fetoha ha eona le ho sebetsa hape ho etsa hore e be karolo ea bohlokoa ea lits'ebetso tse ngata tsa laboratori le lits'ebetso tsa indasteri, e nolofalletsang ho kopanya hantle ha metsoako e fapaneng ea manyolo.Leha ho le joalo, tlhokomeliso e tlameha ho sebelisoa ha ho sebetsoa triflic anhydride, ho latela melaoana e nepahetseng ea polokeho ho netefatsa bophelo bo botle ba k'hemistri le ho thibela likotsi ka laboratoring.