T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate CAS: 124655-09-0
| Nomoro ea lethathamo | XD93413 |
| Lebitso la Sehlahiswa | T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate |
| CAS | 124655-09-0 |
| Foromo ea molek'hulela | C13H24O5 |
| Boima ba Molek'hule | 260.33 |
| Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Assay | 99% mets |
T-Butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate ke motsoako oa lik'hemik'hale o nang le mohaho o rarahaneng o atisang ho sebelisoa ka motsoako oa lintho tse phelang le e le sehlopha se sireletsang lik'hemik'hale tsa lik'hemik'hale tsa lik'hemik'hale.E tsejoa ka bokhoni ba eona ba ho sireletsa lihlopha tsa hydroxyl ka katleho le ho thibela liketso tse sa batleheng nakong ea liphetoho tse sa tšoaneng tsa lik'hemik'hale.E 'ngoe ea lisebelisoa tse ka sehloohong tsa T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5- dihydroxyhexanoate e ka har'a motsoako oa metsoako e rarahaneng ea lintho tse phelang.Lihlopha tsa Hydroxyl li sebetsa haholo 'me li ka ba le maikutlo a sa batleheng nakong ea liphetoho tsa lik'hemik'hale.Ka ho khetha ho sireletsa lihlopha tsena ka T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate moiety, litsebi tsa lik'hemik'hale li ka laola liketso le ho fumana lihlahisoa tse lakatsehang.Ka mor'a hore liphetoho tsa lik'hemik'hale tse lakatsehang li phethoe, sehlopha sa tšireletso se ka tlosoa habonolo, se lumella ho tsosolosoa ha lihlopha tsa pele tsa hydroxyl. 3,5-dihydroxyhexanoate hangata e sebelisoa bakeng sa ts'ireletso ea limolek'hule tsa tsoekere.Tsoekere e na le lihlopha tse ngata tsa hydroxyl tse ka sebetsanang le li-reagents, tse lebisang ho lihlahisoa tse sa batleheng.Ka ho khetha ho sireletsa lihlopha tsena tsa hydroxyl tse nang le T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate, litsebi tsa lik'hemik'hale li ka laola lihlopha tse setseng tsa hydroxyl ntle le tšitiso.Sena se lumella hore ho be le motsoako oa metsoako e rarahaneng ea tsoekere le ho ithuta ho sebelisana ha lik'habohaedreite le protheine kapa motsoako oa glyccoconjugates.Ho feta moo, T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5- Sehlopha sa ts'ireletso sa dihydroxyhexanoate se atisa ho sebelisoa nakong ea tlhahiso ea lihlahisoa tsa tlhaho, meriana, le metsoako e meng e sebetsang ea biologically.Tšireletso ea eona e sebetsang hantle le ts'ireletso e thusa litsebi tsa lik'hemik'hale ho fumana mefuta e mengata ea limolek'hule tse fapaneng tsa sebopeho.Tšireletso ea lihlopha tse khethehileng tsa hydroxyl e thusa ho laola litsela tsa ho itšoara le ho finyella regioselectivity e lakatsehang kapa stereoelectivity.Qetellong, T-butyl-(3R,5S) -6-hydroxy 3,5-O-isopropylidene 3,5-dihydroxyhexanoate ke Motsoako o fapaneng o sebelisoang haholo k'hemistri ea maiketsetso, haholo ts'ireletsong le ts'ireletsong ea lihlopha tsa hydroxyl.Sebopeho sa eona se ikhethang se lumella tšireletso e khethehileng, e nolofalletsang litsebi tsa k'hemistri ho laola karabelo le ho fumana lihlahisoa tse lakatsehang.Lisebelisoa tsa eona li tloha ho kopanngoeng ha metsoako e rarahaneng ea lintho tse phelang ho ea ho lik'hemik'hale tsa lik'habohaedreite le tlhahiso ea lihlahisoa tsa tlhaho le meriana.Bokhoni ba komporo ea ho sireletsa lihlopha tsa hydroxyl ka katleho bo e etsa sesebelisoa sa bohlokoa likarolong tse fapaneng tsa lipatlisiso le nts'etsopele ea lik'hemik'hale.
