(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine CAS: 132335-44-5
Nomoro ea lethathamo | XD93364 |
Lebitso la Sehlahiswa | (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine |
CAS | 132335-44-5 |
Foromo ea molek'hulela | C9H15NOS |
Boima ba Molek'hule | 185.29 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ke motsoako oa chiral o nang le lisebelisoa tse sa tšoaneng lefapheng la meriana.Kopo e le' ngoe ea bohlokoa ea (S) -(-) -N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine e nts'etsopele ea serotonin reuptake inhibitors (SSRIs) e khethiloeng.SSRIs ke sehlopha sa lithethefatsi tse atisang ho sebelisoa ho phekola khatello ea maikutlo, mathata a ho tšoenyeha le maemo a mang a bophelo bo botle ba kelello.Motsoako ona o sebetsa e le selelekela kapa lintho tse qalang ka har'a motsoako oa li-serotonin reuptake inhibitors tse khethiloeng, tse lumellang nts'etsopele ea li-enantiomers tse nang le thepa e ntlafalitsoeng ea kalafo.Ka ho kenyelletsa (S) - (-) -N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine sebopeho sa lithethefatsi, bafuputsi ba ka fetola thepa ea eona ea meriana, joalo ka kamano ea eona le lipalangoang tsa serotonin, ho fella ka katleho e ntlafetseng le litla-morao tse fokotsehileng.Ho phaella moo, (S) - (-) -N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine e ka sebelisoa e le mohaho oa mohaho ha ho etsoa lihlahisoa tse ling tsa bioactive. metsoako.Sebopeho sa eona sa chiral le sebopeho se feto-fetohang se etsa hore e be sesebelisoa sa bohlokoa sa ho qala kaho ea limolek'hule tse rarahaneng.Bafuputsi ba ka sebetsa libaka tse fapaneng tsa molek'hule ho hlahisa lihlopha tse fapaneng kapa ho fetola stereochemistry ea eona ho theha bonkgetheng ba litlhare tse ncha. e ithutiloe bakeng sa tšebeliso ea eona e ka bang teng kalafong ea lefu la Parkinson.Lipatlisiso li bontšitse hore motsoako ona o bonts'a ts'ebetso ea dopamine agonist, ho bolelang hore e ka susumetsa li-receptor tsa dopamine, tse atisang ho angoa ke lefu la Parkinson.E ka 'na ea e-ba le matla a phekolo ho fokotsa matšoao a amanang le lefu lena la neurodegenerative.Ho bohlokoa ho hlokomela hore (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine ke e matla. motsoako, 'me tšebeliso ea eona e lokela ho sebetsoa ka hloko.Bafuputsi le litsebi tse sebetsanang le motsoako ona ba hloka ho latela tataiso le mekhoa ea ts'ireletso ho netefatsa ts'ebetso e nepahetseng le ho fokotsa likotsi.Ka kakaretso, (S) -(-) -N,N-Dimethyl-3-hydroxy-3-(2-thienyl ) propanamine ke motsoako oa bohlokoa ho nts'etsopele ea serotonin reuptake inhibitors e khethiloeng le limolek'hule tse ling tsa bioactive.Sebopeho sa eona sa chiral, sebopeho se feto-fetohang, le mesebetsi e ka bang teng ea kalafo li e etsa motheo oa bohlokoa lipatlisisong tsa meriana.Ho tsoela pele ho ithuta le ho hlahloba (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine e ka kenya letsoho ho nts'etsopele ea lithethefatsi tse ncha le phekolo e ka bang teng bakeng sa mafu a sa tšoaneng.