Lihlahisoa

S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride, e tsejoang hape e le S-(+)-Clopidogrel, ke motsoako oa meriana o nang le foromo ea lik'hemik'hale ea C16H16ClNO2S·HCl. Ke motsoako oa "chiral derivative" oa clopidogrel, e leng moriana oa bohlokoa oa antiplatelet. motsoako oa ho etsoa ha lithethefatsi tsa pelo, haholo-holo li-antiplatelet agents. E fana ka liphello tsa eona tsa phekolo ka ho thibela platelet aggregation, ho thibela ho thehoa ha mali, le ho fokotsa kotsi ea liketsahalo tsa pelo le methapo ea pelo. Ka ho tlamella ka mokhoa o ke keng oa fetoloa ho receptor ena, S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride e thibela tšebetso ea platelet le ho thibela sebopeho. Mokhoa ona oa ts'ebetso o etsa hore e be moriana oa bohlokoa bakeng sa ho thibela liketsahalo tsa thrombotic ho bakuli ba kotsing e kholo, joalo ka ba nang le nalane ea acute coronary syndrome, ischemic stroke, kapa peripheral artery disease.S-(+) -Methyl- (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride hangata e tsamaisoa ka molomo ka mokhoa oa matlapa kapa li-capsules.Ka mor'a ho kenngoa, e fetoha phetoho ea metabolism sebeteng ho hlahisa metabolite ea eona e sebetsang.Metabolite ena e sebetsang e tlama ka mokhoa o ke keng oa khutlisoa ho receptor ea P2Y12, e fana ka litlamorao tsa eona tsa antiplatelet ka nako e telele.Motsoako hangata o laeloa hang ka letsatsi, e ka ba kalafo e ikemetseng kapa hammoho le litlhare tse ling tsa antiplatelet, joalo ka aspirin. Ke habohlokoa ho hlokomela hore S-(+) -Methyl-(2-chlorophenyl)[(2-(2) -thienyl)amino] acetate hydrochloride e lokela ho sebelisoa feela tlas'a tataiso ea setsebi sa tlhokomelo ea bophelo, kaha ts'ebeliso ea eona e ka ba le bokhoni.