leqephe_banner

Lihlahisoa

(S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone CAS: 915095-87-3

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD93368
Cas: 915095-87-3
Foromo ea molek'hule: C17H14ClIO3
Boima ba Molek'hule: 428.65
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana:  
Sephutheloana sa Bongata: Kopa Quote

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD93368
Lebitso la Sehlahiswa (S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone
CAS 915095-87-3
Foromo ea molek'hulela C17H14ClIO3
Boima ba Molek'hule 428.65
Lintlha tsa polokelo Ambient

 

Tlhaloso ea Sehlahisoa

Ponahalo Phofo e tšoeu
Assay 99% mets

 

(S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone, e tsejoang hape e le CF3-112, ke motsoako oa lik'hemik'hale o nang le lits'ebetso tse' maloa tsa bohlokoa lefapheng la k'hemistri ea bongaka le lithethefatsi. ntshetsopele.E 'ngoe ea litšebeliso tse kholo tsa CF3-112 ke e le kinase inhibitor.Kinase ke li-enzyme tse laolang lits'ebetso tse fapaneng tsa lisele tsa 'mele, ho kenyelletsa kholo ea lisele, karohano le puisano.Dysregulation of kinases hangata e amahanngoa le mafu a kang mofetše le mathata a autoimmune.CF3-112 e fumanoe e bonts'a ts'ebetso e matla ea thibelo khahlanong le li-kinase tse itseng, e leng se etsang hore e be mokhethoa ea tšepisang bakeng sa nts'etsopele ea liphekolo tse lebisitsoeng. hangata li hlahisoa ka bongata liseleng tsa mofetše.Ka ho khetha le ho thibela li-kinase tsena, CF3-112 e ka thusa ho emisa ho ata ka potlako ha lisele tsa mofetše le ho fana ka monyetla oa ho fana ka molemo oa phekolo. mafu a kang acute myeloid leukemia (AML) le myeloproliferative neoplasms.Ho thibela li-kinase tsena ka CF3-112 ho na le monyetla oa ho senya litsela tse tsamaisang kholo le ho phela ha lisele tsa mofetše, ho fana ka menyetla e mecha ea phekolo ea mafu ana. - liphello tsa ho ruruha.Ho ruruha ke karabelo e rarahaneng ea likokoana-hloko e phethang karolo ea maloetse a mangata, ho kenyelletsa le mathata a autoimmune le maemo a sa foleng a ho ruruha.CF3-112 e bontšitse tšepiso e le inhibitor ea litsela tse itseng tsa ho ruruha, tse ka 'nang tsa fana ka mokhoa oa phekolo bakeng sa ho laola maemo ana.Le hoja CF3-112 e na le bokhoni bo boholo, ke habohlokoa ho hlokomela hore lipatlisiso tse eketsehileng le tsoelo-pele lia hlokahala ho utloisisa ka botlalo katleho ea eona, polokeho. profil, le ts'ebeliso e nepahetseng.Joalo ka motsoako ofe kapa ofe, ho hlokahala liteko tse matla le lithuto tsa pele ho nako pele e ka tsoela pele ho ea litekong tsa kliniki tsa batho.Ts'ebetso ea eona ea "kinase inhibitory", haholoholo khahlano le Aurora kinases, FLT3, le JAK2, e e beha e le mokhethoa ea ka bang teng bakeng sa nts'etsopele ea liphekolo tse lebisitsoeng bakeng sa mofetše le malignancies a mali.Lintho tsa eona tse khahlanong le ho ruruha li boetse li fana ka maikutlo a hore ho ka sebelisoa mekhoa ea ho laola mafu a autoimmune le maemo a sa foleng a ho ruruha.Leha ho le joalo, lipatlisiso tse ling lia hlokahala ho notlolla bokhoni ba eona bo felletseng ba kalafo le ho lekola polokeho le katleho ea eona.


  • E fetileng:
  • E 'ngoe:

  • Koala

    (S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone CAS: 915095-87-3