Niacinamide Cas: 98-92-0
Nomoro ea lethathamo | XD91246 |
Lebitso la Sehlahiswa | "Niacinamide" |
CAS | 98-92-0 |
Foromo ea molek'hulela | C6H6N2O |
Boima ba Molek'hule | 122.12 |
Lintlha tsa polokelo | Ambient |
Khoutu ea Lekhetho e Kopantsoeng | 29362900 |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu kapa e batlang e le tšoeu ea kristale kapa kristale e se nang mebala |
Assay | ≥99% |
Melting Point | 128°C ~ 131°C |
Boitsebiso | E ntle |
pH | 6.0 ~ 7.5 |
Tahlehelo ka ho Omisa | ≤0.5% |
Molora oa Sulfate | ≤0.1% |
Ho Hlakola ha Tharollo | Hlakileng |
Tšepe e boima | ≤0.003% |
'Mala oa tharollo | ≤BY7 |
Niacinamide e boetse e bitsoa nicotinamide, vithamine B3, kapa vithamine PP, ke mofuta oa livithamini tse qhibilihang metsing, ke tsa livithamini tsa B, joalo ka coenzyme Ⅰ, nicotinamide adenine dinucleotide (NAD) le coenzyme Ⅱ (nicotinamide adenine dinucleotide phosphate, NADP) ka sebopeho sa 'mele oa motho mefuta ena e' meli ea coenzyme nicotinamide partial hydrogenation le dehydrogenation properties tsa reversible, E bapala karolo ea ho fetisa hydrogen ho biooxidation 'me e ka khothalletsa phefumoloho ea lisele, ts'ebetso ea biooxidation le metabolism, e leng ea bohlokoa haholo bakeng sa ho boloka botšepehi ba dinama tse tlwaelehileng, haholo-holo letlalo, pampitšana tshilong ya dijo le tsamaiso ea methapo.Ha ho haella, phefumoloho le metabolism ea lisele li ameha 'me pellagra e bakoa, kahoo sehlahisoa sena se sebelisoa haholo-holo ho thibela le ho phekola pellagra, stomatitis, glossitis joalo-joalo.
Niacinamide e boetse e hlahisoa liphoofolong tse sebelisang niacinamide le niacin tlas'a maemo a mangata a acoustic.Pellagra e etsahala ha 'mele o haelloa ke niacin le nicotinamide.Kahoo ba ka thibela pellagra.Li bapala karolo ea metabolism ea liprotheine le tsoekere, ho ntlafatsa phepo ea batho le liphoofolo.Ho phaella ho meriana, empa hape le palo e kholo ea lijo le lisebelisoa tsa lijo.Matla a tlhahiso ea lefatše a feta lithane tse 30,000.Japane, niacinamide e sebelisoa meriana bakeng sa 40% le lisebelisoa tsa lijo bakeng sa 50%.Li-additives tsa lijo li etsa karolo ea 10%.Asiti ea Nicotinic le nicotinamide ha li chefo 'me hangata li fumaneha sebeteng sa liphoofolo, liphio, tomoso le tsoekere ea raese ka mokhoa oa tlhaho.LD50 ea nicotinamide bakeng sa ente ea subcutaneous ho likhoto e ne e le 1.7 g/kg.
Sebelisa: meriana ea vithamine, e kenya letsoho ts'ebetsong ea metabolism ea 'mele, e sebelisetsoang ho thibela le ho phekola khaello ea niacin e kang pellagra.
Sebelisa: bakeng sa lihlahisoa tsa tlhokomelo ea letlalo li ka thibela letlalo ho ba mahlahahlaha, li boloka bophelo bo botle ba lisele tsa letlalo, li khothalletsa ho soeufala ha letlalo.E sebelisoa tlhokomelong ea moriri e ka khothalletsa phallo ea mali ea hlooho, li-follicles tsa moriri tse phetseng hantle, ho khothalletsa ho hōla ha moriri, ho thibela lefatla.
Kopo: Patlisiso ea biochemical;Motsoako oa limatlafatsi oa setso sa lithane;Meriana ea bongaka Chemicalbook ke sehlopha sa vithamine B, se sebelisetsoang ho thibela le ho phekola pellagra, stomatitis, glossia le mafu a mang.
Sebelisa: Ho tšoana le niacin.Ho qhibiliha ha metsi ho molemo ho feta niacin, empa ho bonolo ho theha e rarahaneng ka vithamine C le agglomerate.Tekanyetso ea 30-80 mg / kg.
Morero: Patlisiso ea biochemical.Ho ile ha lokisoa mokhoa oa ho etsa lithane.Indasteri ea meriana.
Tšebeliso: motsoako oa amide oa vithamine B3 le PARP inhibitors.